Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach

Multidrug‐resistant bacterial infections are commonly treated with glycopeptide antibiotics such as teicoplanin. This drug inhibits bacterial cell‐wall biosynthesis by binding and sequestering a cell‐wall precursor: a D‐alanine‐containing peptide. A carrier‐protein strategy was used to crystallize t...

Ausführliche Beschreibung