Synthesis, characterization and in vitro studies of doxorubicin-loaded magnetic nanoparticles grafted to smart copolymers on A549 lung cancer cell line

The aim of present study was to develop the novel methods for chemical and physical modification of superparamagnetic iron oxide nanoparticles (SPIONs) with polymers via covalent bonding entrapment. These modified SPIONs were used for encapsulation of anticancer drug doxorubicin. At first approach s...

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Veröffentlicht in:	Journal of nanobiotechnology 2012-12, Vol.10 (1), p.46-46
Hauptverfasser:	Akbarzadeh, Abolfazl, Samiei, Mohammad, Joo, Sang Woo, Anzaby, Maryam, Hanifehpour, Younes, Nasrabadi, Hamid Tayefi, Davaran, Soodabeh
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Anthracyclines Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacokinetics Cancer Cancer therapies Cell Line, Tumor Cell Survival - drug effects Chemotherapy Colleges & universities Cytotoxicity Doxorubicin - administration & dosage Doxorubicin - chemistry Doxorubicin - pharmacokinetics Drug Carriers - chemical synthesis Drug Carriers - chemistry Ferric oxide Fourier transforms Humans Hydrogen-Ion Concentration Iron compounds Lung cancer Magnetic properties Magnetite Nanoparticles - administration & dosage Magnetite Nanoparticles - chemistry Nanomaterials Nanoparticles NMR Nuclear magnetic resonance Oncology, Experimental Phase transitions Polymerization Polymers - chemistry Silane Spectroscopy, Fourier Transform Infrared Temperature
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