The RLF-B Component of the Replication Licensing System is Distinct from Cdc6 and Functions After Cdc6 has Bound to Chromatin

Replication Licensing Factor (RLF) was originally defined as an essential initiation factor whose regulation prevents re-replication of DNA in a single cell cycle [ 1 , reviewed in 2 ]. It is required for the initiation of DNA replication, binds to chromatin early in the cell cycle, is removed from...

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Veröffentlicht in:Current biology 1999-02, Vol.9 (4), p.211-214
Hauptverfasser: Tada, Shusuke, Chong, James P.J., Mahbubani, Hiro M., Blow, J. Julian
Format: Artikel
Sprache:eng
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