Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas

We compared aortic stiffness, aortic impedance and pressure from wave reflections in the setting of bicuspid aortic valve (BAV) to the tricuspid aortic valve (TAV) in the absence of proximal aortic dilation. We hypothesized BAV is associated with abnormal arterial stiffness. Ten BAV subjects (47 ± 4...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMC cardiovascular disorders 2013-03, Vol.13 (1), p.19-19, Article 19
Hauptverfasser: Warner, Patrick J, Al-Quthami, Adeeb, Brooks, Erica L, Kelley-Hedgepeth, Alyson, Patvardhan, Eshan, Kuvin, Jeffrey T, Heffernan, Kevin S, Huggins, Gordon S
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 19
container_issue 1
container_start_page 19
container_title BMC cardiovascular disorders
container_volume 13
creator Warner, Patrick J
Al-Quthami, Adeeb
Brooks, Erica L
Kelley-Hedgepeth, Alyson
Patvardhan, Eshan
Kuvin, Jeffrey T
Heffernan, Kevin S
Huggins, Gordon S
description We compared aortic stiffness, aortic impedance and pressure from wave reflections in the setting of bicuspid aortic valve (BAV) to the tricuspid aortic valve (TAV) in the absence of proximal aortic dilation. We hypothesized BAV is associated with abnormal arterial stiffness. Ten BAV subjects (47 ± 4 years, 6 male) and 13 TAV subjects (46 ± 4 years, 10 male) without significant aortic valve disease were prospectively recruited. Characteristic impedance (Zc) was derived from echocardiographic images and pulse wave Doppler of the left ventricular outflow tract. Applanation tonometry was performed to obtain pulse wave velocity (PWV) at several sites as measures of arterial stiffness and augmentation index (AIx) as a measure of wave reflection. There were no significant differences between BAV and TAV subjects with regard to heart rate or blood pressure. Zc was similar between BAV and TAV subjects (p=0.25) as was carotid-femoral pulse wave velocity (cf-PWV) and carotid-radial PWV (cr-PWV) between BAV and TAV subjects (p=0.99). Carotid AIx was significantly higher in BAV patients compared with TAV patients (14.3 ± 4.18% versus -3.02 ± 3.96%, p=0.007). Aortic stiffness and impedance is similar between subjects with BAV and TAV with normal aortic dimensions. The significantly higher carotid AIx in BAV, a proxy of increased pressure from wave reflections, may reflect abnormal vascular function distal to the aorta.
doi_str_mv 10.1186/1471-2261-13-19
format Article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3602003</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A534587621</galeid><sourcerecordid>A534587621</sourcerecordid><originalsourceid>FETCH-LOGICAL-c488t-50e43bab3415822c26ab39c5a0be0ec0b89d955ec0a30788f428aa5d5b4486933</originalsourceid><addsrcrecordid>eNptkstv1DAQxi1ERUvhzA1Z4sIlrZ-JfUFaVeUhVeICZ8txJluvEjvYyVL--zp9LC1CPng085vPM9aH0DtKzihV9TkVDa0Yq2lFeUX1C3RyyLx8Eh-j1znvCKGNIvoVOmZc6FoRcYJ2m2U7Qpjt7GPAPnRwg23osI1p9g7n2fd9gJxLCbfeLXnyh-LeDnvAU2ktAhn_9vM1DjFUnR_sDB2eUrzxox3ueJvfoKPeDhnePtyn6Ofnyx8XX6ur71--XWyuKieUmitJQPDWtlxQqRhzrC6xdtKSFgg40irdaSlLZDlplOoFU9bKTrZCqFpzfoo-3etOSztC58pwyQ5mSmWW9MdE683zSvDXZhv3hteEEbIKfHwQSPHXAnk2o88OhsEGiEs2lJev10TdoR_-QXdxSaGst1KNJFJT9pfa2gGMD30s77pV1GwkF1I1NaOFOvsPVU4Ho3cxQO9L_lnD-X2DSzHnBP1hR0rMag-zGsCsBijTGKpLx_unX3PgH_3AbwFpxLVU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1317505912</pqid></control><display><type>article</type><title>Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>Springer Nature OA Free Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>SpringerLink Journals - AutoHoldings</source><creator>Warner, Patrick J ; Al-Quthami, Adeeb ; Brooks, Erica L ; Kelley-Hedgepeth, Alyson ; Patvardhan, Eshan ; Kuvin, Jeffrey T ; Heffernan, Kevin S ; Huggins, Gordon S</creator><creatorcontrib>Warner, Patrick J ; Al-Quthami, Adeeb ; Brooks, Erica L ; Kelley-Hedgepeth, Alyson ; Patvardhan, Eshan ; Kuvin, Jeffrey T ; Heffernan, Kevin S ; Huggins, Gordon S</creatorcontrib><description>We compared aortic stiffness, aortic impedance and pressure from wave reflections in the setting of bicuspid aortic valve (BAV) to the tricuspid aortic valve (TAV) in the absence of proximal aortic dilation. We hypothesized BAV is associated with abnormal arterial stiffness. Ten BAV subjects (47 ± 4 years, 6 male) and 13 TAV subjects (46 ± 4 years, 10 male) without significant aortic valve disease were prospectively recruited. Characteristic impedance (Zc) was derived from echocardiographic images and pulse wave Doppler of the left ventricular outflow tract. Applanation tonometry was performed to obtain pulse wave velocity (PWV) at several sites as measures of arterial stiffness and augmentation index (AIx) as a measure of wave reflection. There were no significant differences between BAV and TAV subjects with regard to heart rate or blood pressure. Zc was similar between BAV and TAV subjects (p=0.25) as was carotid-femoral pulse wave velocity (cf-PWV) and carotid-radial PWV (cr-PWV) between BAV and TAV subjects (p=0.99). Carotid AIx was significantly higher in BAV patients compared with TAV patients (14.3 ± 4.18% versus -3.02 ± 3.96%, p=0.007). Aortic stiffness and impedance is similar between subjects with BAV and TAV with normal aortic dimensions. The significantly higher carotid AIx in BAV, a proxy of increased pressure from wave reflections, may reflect abnormal vascular function distal to the aorta.</description><identifier>ISSN: 1471-2261</identifier><identifier>EISSN: 1471-2261</identifier><identifier>DOI: 10.1186/1471-2261-13-19</identifier><identifier>PMID: 23496804</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adult ; Analysis ; Aorta ; Aorta - diagnostic imaging ; Aorta - physiopathology ; Aortic valve ; Aortic Valve - abnormalities ; Aortic Valve - diagnostic imaging ; Aortic Valve - physiopathology ; Arterial Pressure ; Bicuspid Aortic Valve Disease ; Chi-Square Distribution ; Comparative analysis ; Consent ; Coronary vessels ; Echocardiography, Doppler, Pulsed ; Female ; Flow velocity ; Heart beat ; Heart Rate ; Heart valve diseases ; Heart Valve Diseases - diagnostic imaging ; Heart Valve Diseases - physiopathology ; Humans ; Hypotheses ; Male ; Manometry ; Middle Aged ; Physiological aspects ; Predictive Value of Tests ; Prospective Studies ; Pulse Wave Analysis ; Studies ; Vascular Stiffness ; Veins &amp; arteries</subject><ispartof>BMC cardiovascular disorders, 2013-03, Vol.13 (1), p.19-19, Article 19</ispartof><rights>COPYRIGHT 2013 BioMed Central Ltd.</rights><rights>2013 Warner et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright ©2013 Warner et al.; licensee BioMed Central Ltd. 2013 Warner et al.; licensee BioMed Central Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c488t-50e43bab3415822c26ab39c5a0be0ec0b89d955ec0a30788f428aa5d5b4486933</citedby><cites>FETCH-LOGICAL-c488t-50e43bab3415822c26ab39c5a0be0ec0b89d955ec0a30788f428aa5d5b4486933</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602003/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602003/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23496804$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Warner, Patrick J</creatorcontrib><creatorcontrib>Al-Quthami, Adeeb</creatorcontrib><creatorcontrib>Brooks, Erica L</creatorcontrib><creatorcontrib>Kelley-Hedgepeth, Alyson</creatorcontrib><creatorcontrib>Patvardhan, Eshan</creatorcontrib><creatorcontrib>Kuvin, Jeffrey T</creatorcontrib><creatorcontrib>Heffernan, Kevin S</creatorcontrib><creatorcontrib>Huggins, Gordon S</creatorcontrib><title>Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas</title><title>BMC cardiovascular disorders</title><addtitle>BMC Cardiovasc Disord</addtitle><description>We compared aortic stiffness, aortic impedance and pressure from wave reflections in the setting of bicuspid aortic valve (BAV) to the tricuspid aortic valve (TAV) in the absence of proximal aortic dilation. We hypothesized BAV is associated with abnormal arterial stiffness. Ten BAV subjects (47 ± 4 years, 6 male) and 13 TAV subjects (46 ± 4 years, 10 male) without significant aortic valve disease were prospectively recruited. Characteristic impedance (Zc) was derived from echocardiographic images and pulse wave Doppler of the left ventricular outflow tract. Applanation tonometry was performed to obtain pulse wave velocity (PWV) at several sites as measures of arterial stiffness and augmentation index (AIx) as a measure of wave reflection. There were no significant differences between BAV and TAV subjects with regard to heart rate or blood pressure. Zc was similar between BAV and TAV subjects (p=0.25) as was carotid-femoral pulse wave velocity (cf-PWV) and carotid-radial PWV (cr-PWV) between BAV and TAV subjects (p=0.99). Carotid AIx was significantly higher in BAV patients compared with TAV patients (14.3 ± 4.18% versus -3.02 ± 3.96%, p=0.007). Aortic stiffness and impedance is similar between subjects with BAV and TAV with normal aortic dimensions. The significantly higher carotid AIx in BAV, a proxy of increased pressure from wave reflections, may reflect abnormal vascular function distal to the aorta.</description><subject>Adult</subject><subject>Analysis</subject><subject>Aorta</subject><subject>Aorta - diagnostic imaging</subject><subject>Aorta - physiopathology</subject><subject>Aortic valve</subject><subject>Aortic Valve - abnormalities</subject><subject>Aortic Valve - diagnostic imaging</subject><subject>Aortic Valve - physiopathology</subject><subject>Arterial Pressure</subject><subject>Bicuspid Aortic Valve Disease</subject><subject>Chi-Square Distribution</subject><subject>Comparative analysis</subject><subject>Consent</subject><subject>Coronary vessels</subject><subject>Echocardiography, Doppler, Pulsed</subject><subject>Female</subject><subject>Flow velocity</subject><subject>Heart beat</subject><subject>Heart Rate</subject><subject>Heart valve diseases</subject><subject>Heart Valve Diseases - diagnostic imaging</subject><subject>Heart Valve Diseases - physiopathology</subject><subject>Humans</subject><subject>Hypotheses</subject><subject>Male</subject><subject>Manometry</subject><subject>Middle Aged</subject><subject>Physiological aspects</subject><subject>Predictive Value of Tests</subject><subject>Prospective Studies</subject><subject>Pulse Wave Analysis</subject><subject>Studies</subject><subject>Vascular Stiffness</subject><subject>Veins &amp; arteries</subject><issn>1471-2261</issn><issn>1471-2261</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkstv1DAQxi1ERUvhzA1Z4sIlrZ-JfUFaVeUhVeICZ8txJluvEjvYyVL--zp9LC1CPng085vPM9aH0DtKzihV9TkVDa0Yq2lFeUX1C3RyyLx8Eh-j1znvCKGNIvoVOmZc6FoRcYJ2m2U7Qpjt7GPAPnRwg23osI1p9g7n2fd9gJxLCbfeLXnyh-LeDnvAU2ktAhn_9vM1DjFUnR_sDB2eUrzxox3ueJvfoKPeDhnePtyn6Ofnyx8XX6ur71--XWyuKieUmitJQPDWtlxQqRhzrC6xdtKSFgg40irdaSlLZDlplOoFU9bKTrZCqFpzfoo-3etOSztC58pwyQ5mSmWW9MdE683zSvDXZhv3hteEEbIKfHwQSPHXAnk2o88OhsEGiEs2lJev10TdoR_-QXdxSaGst1KNJFJT9pfa2gGMD30s77pV1GwkF1I1NaOFOvsPVU4Ho3cxQO9L_lnD-X2DSzHnBP1hR0rMag-zGsCsBijTGKpLx_unX3PgH_3AbwFpxLVU</recordid><startdate>20130315</startdate><enddate>20130315</enddate><creator>Warner, Patrick J</creator><creator>Al-Quthami, Adeeb</creator><creator>Brooks, Erica L</creator><creator>Kelley-Hedgepeth, Alyson</creator><creator>Patvardhan, Eshan</creator><creator>Kuvin, Jeffrey T</creator><creator>Heffernan, Kevin S</creator><creator>Huggins, Gordon S</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130315</creationdate><title>Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas</title><author>Warner, Patrick J ; Al-Quthami, Adeeb ; Brooks, Erica L ; Kelley-Hedgepeth, Alyson ; Patvardhan, Eshan ; Kuvin, Jeffrey T ; Heffernan, Kevin S ; Huggins, Gordon S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c488t-50e43bab3415822c26ab39c5a0be0ec0b89d955ec0a30788f428aa5d5b4486933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Analysis</topic><topic>Aorta</topic><topic>Aorta - diagnostic imaging</topic><topic>Aorta - physiopathology</topic><topic>Aortic valve</topic><topic>Aortic Valve - abnormalities</topic><topic>Aortic Valve - diagnostic imaging</topic><topic>Aortic Valve - physiopathology</topic><topic>Arterial Pressure</topic><topic>Bicuspid Aortic Valve Disease</topic><topic>Chi-Square Distribution</topic><topic>Comparative analysis</topic><topic>Consent</topic><topic>Coronary vessels</topic><topic>Echocardiography, Doppler, Pulsed</topic><topic>Female</topic><topic>Flow velocity</topic><topic>Heart beat</topic><topic>Heart Rate</topic><topic>Heart valve diseases</topic><topic>Heart Valve Diseases - diagnostic imaging</topic><topic>Heart Valve Diseases - physiopathology</topic><topic>Humans</topic><topic>Hypotheses</topic><topic>Male</topic><topic>Manometry</topic><topic>Middle Aged</topic><topic>Physiological aspects</topic><topic>Predictive Value of Tests</topic><topic>Prospective Studies</topic><topic>Pulse Wave Analysis</topic><topic>Studies</topic><topic>Vascular Stiffness</topic><topic>Veins &amp; arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Warner, Patrick J</creatorcontrib><creatorcontrib>Al-Quthami, Adeeb</creatorcontrib><creatorcontrib>Brooks, Erica L</creatorcontrib><creatorcontrib>Kelley-Hedgepeth, Alyson</creatorcontrib><creatorcontrib>Patvardhan, Eshan</creatorcontrib><creatorcontrib>Kuvin, Jeffrey T</creatorcontrib><creatorcontrib>Heffernan, Kevin S</creatorcontrib><creatorcontrib>Huggins, Gordon S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMC cardiovascular disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Warner, Patrick J</au><au>Al-Quthami, Adeeb</au><au>Brooks, Erica L</au><au>Kelley-Hedgepeth, Alyson</au><au>Patvardhan, Eshan</au><au>Kuvin, Jeffrey T</au><au>Heffernan, Kevin S</au><au>Huggins, Gordon S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas</atitle><jtitle>BMC cardiovascular disorders</jtitle><addtitle>BMC Cardiovasc Disord</addtitle><date>2013-03-15</date><risdate>2013</risdate><volume>13</volume><issue>1</issue><spage>19</spage><epage>19</epage><pages>19-19</pages><artnum>19</artnum><issn>1471-2261</issn><eissn>1471-2261</eissn><abstract>We compared aortic stiffness, aortic impedance and pressure from wave reflections in the setting of bicuspid aortic valve (BAV) to the tricuspid aortic valve (TAV) in the absence of proximal aortic dilation. We hypothesized BAV is associated with abnormal arterial stiffness. Ten BAV subjects (47 ± 4 years, 6 male) and 13 TAV subjects (46 ± 4 years, 10 male) without significant aortic valve disease were prospectively recruited. Characteristic impedance (Zc) was derived from echocardiographic images and pulse wave Doppler of the left ventricular outflow tract. Applanation tonometry was performed to obtain pulse wave velocity (PWV) at several sites as measures of arterial stiffness and augmentation index (AIx) as a measure of wave reflection. There were no significant differences between BAV and TAV subjects with regard to heart rate or blood pressure. Zc was similar between BAV and TAV subjects (p=0.25) as was carotid-femoral pulse wave velocity (cf-PWV) and carotid-radial PWV (cr-PWV) between BAV and TAV subjects (p=0.99). Carotid AIx was significantly higher in BAV patients compared with TAV patients (14.3 ± 4.18% versus -3.02 ± 3.96%, p=0.007). Aortic stiffness and impedance is similar between subjects with BAV and TAV with normal aortic dimensions. The significantly higher carotid AIx in BAV, a proxy of increased pressure from wave reflections, may reflect abnormal vascular function distal to the aorta.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>23496804</pmid><doi>10.1186/1471-2261-13-19</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1471-2261
ispartof BMC cardiovascular disorders, 2013-03, Vol.13 (1), p.19-19, Article 19
issn 1471-2261
1471-2261
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3602003
source MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central Open Access; Springer Nature OA Free Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; SpringerLink Journals - AutoHoldings
subjects Adult
Analysis
Aorta
Aorta - diagnostic imaging
Aorta - physiopathology
Aortic valve
Aortic Valve - abnormalities
Aortic Valve - diagnostic imaging
Aortic Valve - physiopathology
Arterial Pressure
Bicuspid Aortic Valve Disease
Chi-Square Distribution
Comparative analysis
Consent
Coronary vessels
Echocardiography, Doppler, Pulsed
Female
Flow velocity
Heart beat
Heart Rate
Heart valve diseases
Heart Valve Diseases - diagnostic imaging
Heart Valve Diseases - physiopathology
Humans
Hypotheses
Male
Manometry
Middle Aged
Physiological aspects
Predictive Value of Tests
Prospective Studies
Pulse Wave Analysis
Studies
Vascular Stiffness
Veins & arteries
title Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T11%3A53%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Augmentation%20index%20and%20aortic%20stiffness%20in%20bicuspid%20aortic%20valve%20patients%20with%20non-dilated%20proximal%20aortas&rft.jtitle=BMC%20cardiovascular%20disorders&rft.au=Warner,%20Patrick%20J&rft.date=2013-03-15&rft.volume=13&rft.issue=1&rft.spage=19&rft.epage=19&rft.pages=19-19&rft.artnum=19&rft.issn=1471-2261&rft.eissn=1471-2261&rft_id=info:doi/10.1186/1471-2261-13-19&rft_dat=%3Cgale_pubme%3EA534587621%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1317505912&rft_id=info:pmid/23496804&rft_galeid=A534587621&rfr_iscdi=true