Multivalent Interactions: Synthesis and Evaluation of Melanotropin MultimersTools for Melanoma Targeting

To develop agents for early detection and selective treatment of melanomas, high affinity and high specificity molecular tools are required. Enhanced specificity may be obtained by simultaneously binding to multiple cell surface targets via the use of multimeric analogues of naturally occurring liga...

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Veröffentlicht in:ACS medicinal chemistry letters 2013-01, Vol.4 (1), p.98-102
Hauptverfasser: Brabez, Nabila, Saunders, Kara, Nguyen, Kevin L, Jayasundera, Thanuja, Weber, Craig, Lynch, Ronald M, Chassaing, Gerard, Lavielle, Solange, Hruby, Victor J
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Sprache:eng
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