IL-1R1 is required for dendritic cell-mediated T cell reactivation within the CNS during West Nile virus encephalitis

Infections of the central nervous system (CNS) with cytopathic viruses require efficient T cell responses to promote viral clearance, limit immunopathology, and enhance survival. We found that IL-1R1 is critical for effector T cell reactivation and limits inflammation within the CNS during murine We...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Journal of experimental medicine 2013-03, Vol.210 (3), p.503-516
Hauptverfasser: Durrant, Douglas M, Robinette, Michelle L, Klein, Robyn S
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!