22-Oxacalcitriol Prevents Progression of Peritoneal Fibrosis in a Mouse Model

Vitamin D plays an important role in calcium homeostasis and is used to treat secondary hyperparathyroidism among dialysis patients. The biologic activity of vitamin D and its analogs is mediated by vitamin D receptor (VDR), which is distributed widely throughout the body. Recent papers have reveale...

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Veröffentlicht in:	Peritoneal dialysis international 2013-03, Vol.33 (2), p.132-142
Hauptverfasser:	Hirose, Misaki, Nishino, Tomoya, Obata, Yoko, Nakazawa, Masayuki, Nakazawa, Yuka, Furusu, Akira, Abe, Katsushige, Miyazaki, Masanobu, Koji, Takehiko, Kohno, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Calcitriol - analogs & derivatives Calcitriol - therapeutic use Chemokine CCL2 - metabolism Chlorhexidine - analogs & derivatives Collagen Type III - metabolism Disease Models, Animal Male Mice Original Peritoneal Dialysis - adverse effects Peritoneal Fibrosis - etiology Peritoneal Fibrosis - pathology Peritoneal Fibrosis - prevention & control Receptors, Calcitriol - metabolism Smad Proteins, Receptor-Regulated - metabolism Transforming Growth Factor beta - metabolism Vitamins - therapeutic use
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