IS200/IS605 family single-strand transposition: mechanism of IS608 strand transfer

Transposase, TnpA, of the IS200/IS605 family member IS608, catalyses single-strand DNA transposition and is dimeric with hybrid catalytic sites composed of an HUH motif from one monomer and a catalytic Y127 present in an α-helix (αD) from the other (trans configuration). αD is attached to the main b...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nucleic acids research 2013-03, Vol.41 (5), p.3302-3313
Hauptverfasser:	He, Susu, Guynet, Catherine, Siguier, Patricia, Hickman, Alison B, Dyda, Fred, Chandler, Mick, Ton-Hoang, Bao
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acid Substitution Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Base Sequence Biochemistry, Molecular Biology Catalytic Domain Consensus Sequence DNA Cleavage DNA Transposable Elements DNA, Bacterial - genetics Electrophoretic Mobility Shift Assay Escherichia coli Helicobacter pylori - enzymology Helicobacter pylori - genetics Inverted Repeat Sequences Life Sciences Molecular biology Molecular Sequence Data Mutagenesis, Site-Directed Nucleic Acid Enzymes Plasmids - genetics Transposases - chemistry Transposases - genetics Transposases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!