JunD Protects the Liver from Ischemia/Reperfusion Injury by Dampening AP-1 Transcriptional Activation

The AP-1 transcription factor modulates a wide range of cellular processes, including cellular proliferation, programmed cell death, and survival. JunD is a major component of the AP-1 complex following liver ischemia/reperfusion (I/R) injury; however, its precise function in this setting remains un...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2008-03, Vol.283 (11), p.6687-6695
Hauptverfasser:	Marden, Jennifer J., Zhang, Yulong, Oakley, Fredrick D., Zhou, Weihong, Luo, Meihui, Jia, Hong Peng, McCray, Paul B., Yaniv, Moshe, Weitzman, Jonathan B., Engelhardt, John F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Proliferation Genes, Dominant Genes, jun Hepatocytes - metabolism Life Sciences Liver - metabolism Liver - pathology Membrane Glycoproteins - metabolism Mice Mice, Transgenic Mitogen-Activated Protein Kinase 8 - metabolism Models, Biological NADPH Oxidase 2 NADPH Oxidase 4 NADPH Oxidases - metabolism Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - physiology Proto-Oncogene Proteins c-jun Reperfusion Injury - metabolism Transcription Factor AP-1 - metabolism Transcription Factor AP-1 - physiology Transcriptional Activation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!