Trace Amine Associated Receptor 1 Signaling in Activated Lymphocytes

Although most research to date on Trace Amine Associated Receptor 1 (TAAR1) has focused on its role in the brain, it has been recognized since its discovery in 2001 that TAAR1 mRNA is expressed in peripheral tissues as well, suggesting that this receptor may play a role in non-neurological pathways....

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Veröffentlicht in:	Journal of neuroimmune pharmacology 2012-12, Vol.7 (4), p.866-876
Hauptverfasser:	Panas, Michael W., Xie, Zhihua, Panas, Helen N., Hoener, Marius C., Vallender, Eric J., Miller, Gregory M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzamides - pharmacology Biomedical and Life Sciences Biomedicine Blotting, Western Cell Biology Central Nervous System Stimulants - pharmacology Cyclic AMP Response Element-Binding Protein - metabolism Cyclic AMP-Dependent Protein Kinases - metabolism HEK293 Cells Humans Immunology Luciferases - genetics Lymphocyte Activation - physiology Lymphocytes Lymphocytes - physiology Macaca mulatta Methamphetamine Methamphetamine - pharmacology Monkeys & apes Neurosciences NFATC Transcription Factors - metabolism Original Article Pharmacology/Toxicology Protein Kinase C - metabolism Pyrrolidines - pharmacology Receptors, G-Protein-Coupled - physiology Signal Transduction - physiology Transfection Virology
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