Fast synaptic inhibition in spinal sensory processing and pain control

The two amino acids GABA and glycine mediate fast inhibitory neurotransmission in different CNS areas and serve pivotal roles in the spinal sensory processing. Under healthy conditions, they limit the excitability of spinal terminals of primary sensory nerve fibers and of intrinsic dorsal horn neuro...

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Veröffentlicht in:	Physiological reviews 2012-01, Vol.92 (1), p.193-235
Hauptverfasser:	Zeilhofer, Hanns Ulrich, Wildner, Hendrik, Yévenes, Gonzalo E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals gamma-Aminobutyric Acid - physiology Glycine - physiology Humans Interneurons - physiology Nervous system Neurons Neurotransmitter Agents - physiology Neurotransmitters Pain Pain - physiopathology Pathology Posterior Horn Cells - physiology Sensory Receptor Cells - physiology Synaptic Transmission - physiology
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