Out of the lab and into the bathroom: evening short-term exposure to conventional light suppresses melatonin and increases alertness perception
Life in 24-h society relies on the use of artificial light at night that might disrupt synchronization of the endogenous circadian timing system to the solar day. This could have a negative impact on sleep-wake patterns and psychiatric symptoms. The aim of the study was to investigate the influence...
Gespeichert in:
| Veröffentlicht in: | International journal of molecular sciences 2013-01, Vol.14 (2), p.2573-2589 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2589 |
|---|---|
| container_issue | 2 |
| container_start_page | 2573 |
| container_title | International journal of molecular sciences |
| container_volume | 14 |
| creator | Wahnschaffe, Amely Haedel, Sven Rodenbeck, Andrea Stoll, Claudia Rudolph, Horst Kozakov, Ruslan Schoepp, Heinz Kunz, Dieter |
| description | Life in 24-h society relies on the use of artificial light at night that might disrupt synchronization of the endogenous circadian timing system to the solar day. This could have a negative impact on sleep-wake patterns and psychiatric symptoms. The aim of the study was to investigate the influence of evening light emitted by domestic and work place lamps in a naturalistic setting on melatonin levels and alertness in humans. Healthy subjects (6 male, 3 female, 22-33 years) were exposed to constant dim light ( |
| doi_str_mv | 10.3390/ijms14022573 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3588003</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1282839745</sourcerecordid><originalsourceid>FETCH-LOGICAL-c412t-acd315c9aee39521b74082ba0463fcd84605e0c9049e4e3945151e0b8701910e3</originalsourceid><addsrcrecordid>eNpdkU1vFDEMhkcIREvhxhlF4tIDU5yvnQmHSqjio1KlXuAcZbLenawyyZBkKvgV_ctk6VItnGzZj1_ZfpvmNYULzhW8d7spUwGMyY4_aU6pYKwFWHVPj_KT5kXOOwDGmVTPmxPGueyZ6E-b-9ulkLghZUTizUBMWBMXSvxTGEwZU4zTB4J3GFzYkjzGVNqCaSL4c455SUgqbGOoQHExGE-8246F5GWeE-aMmUzoTYl1_qBuE5p93XhMJVSGzJgszvv5l82zjfEZXx3iWfP986dvV1_bm9sv11cfb1orKCutsWtOpVUGkSvJ6NAJ6NlgQKz4xq57sQKJYBUIhaIiQlJJEYa-A6ooID9rLh9052WYcG3r9sl4PSc3mfRLR-P0v53gRr2Nd7o-rgfgVeD8IJDijwVz0ZPLFr03AeOSNWU967nqhKzo2__QXVxSfVWlJFtBdU51lXr3QNkUc064eVyGgt47rY-drvib4wMe4b_W8t_rZ6e3</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1526025797</pqid></control><display><type>article</type><title>Out of the lab and into the bathroom: evening short-term exposure to conventional light suppresses melatonin and increases alertness perception</title><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Wahnschaffe, Amely ; Haedel, Sven ; Rodenbeck, Andrea ; Stoll, Claudia ; Rudolph, Horst ; Kozakov, Ruslan ; Schoepp, Heinz ; Kunz, Dieter</creator><creatorcontrib>Wahnschaffe, Amely ; Haedel, Sven ; Rodenbeck, Andrea ; Stoll, Claudia ; Rudolph, Horst ; Kozakov, Ruslan ; Schoepp, Heinz ; Kunz, Dieter</creatorcontrib><description>Life in 24-h society relies on the use of artificial light at night that might disrupt synchronization of the endogenous circadian timing system to the solar day. This could have a negative impact on sleep-wake patterns and psychiatric symptoms. The aim of the study was to investigate the influence of evening light emitted by domestic and work place lamps in a naturalistic setting on melatonin levels and alertness in humans. Healthy subjects (6 male, 3 female, 22-33 years) were exposed to constant dim light (<10 lx) for six evenings from 7:00 p.m. to midnight. On evenings 2 through 6, 1 h before habitual bedtime, they were also exposed to light emitted by 5 different conventional lamps for 30 min. Exposure to yellow light did not alter the increase of melatonin in saliva compared to dim light baseline during (38 ± 27 pg/mL vs. 39 ± 23 pg/mL) and after light exposure (39 ± 22 pg/mL vs. 44 ± 26 pg/mL). In contrast, lighting conditions including blue components reduced melatonin increase significantly both during (office daylight white: 25 ± 16 pg/mL, bathroom daylight white: 24 ± 10 pg/mL, Planon warm white: 26 ± 14 pg/mL, hall daylight white: 22 ± 14 pg/mL) and after light exposure (office daylight white: 25 ± 15 pg/mL, bathroom daylight white: 23 ± 9 pg/mL, Planon warm white: 24 ± 13 pg/mL, hall daylight white: 22 ± 26 pg/mL). Subjective alertness was significantly increased after exposure to three of the lighting conditions which included blue spectral components in their spectra. Evening exposure to conventional lamps in an everyday setting influences melatonin excretion and alertness perception within 30 min.</description><identifier>ISSN: 1422-0067</identifier><identifier>ISSN: 1661-6596</identifier><identifier>EISSN: 1422-0067</identifier><identifier>DOI: 10.3390/ijms14022573</identifier><identifier>PMID: 23358248</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Alzheimer's disease ; Circadian rhythm ; Electronic mail systems ; Gene expression ; Influence ; Insomnia ; Melatonin ; Mental depression ; Mental disorders ; Physiology ; Sleep</subject><ispartof>International journal of molecular sciences, 2013-01, Vol.14 (2), p.2573-2589</ispartof><rights>Copyright MDPI AG 2013</rights><rights>2013 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c412t-acd315c9aee39521b74082ba0463fcd84605e0c9049e4e3945151e0b8701910e3</citedby><cites>FETCH-LOGICAL-c412t-acd315c9aee39521b74082ba0463fcd84605e0c9049e4e3945151e0b8701910e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588003/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588003/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23358248$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wahnschaffe, Amely</creatorcontrib><creatorcontrib>Haedel, Sven</creatorcontrib><creatorcontrib>Rodenbeck, Andrea</creatorcontrib><creatorcontrib>Stoll, Claudia</creatorcontrib><creatorcontrib>Rudolph, Horst</creatorcontrib><creatorcontrib>Kozakov, Ruslan</creatorcontrib><creatorcontrib>Schoepp, Heinz</creatorcontrib><creatorcontrib>Kunz, Dieter</creatorcontrib><title>Out of the lab and into the bathroom: evening short-term exposure to conventional light suppresses melatonin and increases alertness perception</title><title>International journal of molecular sciences</title><addtitle>Int J Mol Sci</addtitle><description>Life in 24-h society relies on the use of artificial light at night that might disrupt synchronization of the endogenous circadian timing system to the solar day. This could have a negative impact on sleep-wake patterns and psychiatric symptoms. The aim of the study was to investigate the influence of evening light emitted by domestic and work place lamps in a naturalistic setting on melatonin levels and alertness in humans. Healthy subjects (6 male, 3 female, 22-33 years) were exposed to constant dim light (<10 lx) for six evenings from 7:00 p.m. to midnight. On evenings 2 through 6, 1 h before habitual bedtime, they were also exposed to light emitted by 5 different conventional lamps for 30 min. Exposure to yellow light did not alter the increase of melatonin in saliva compared to dim light baseline during (38 ± 27 pg/mL vs. 39 ± 23 pg/mL) and after light exposure (39 ± 22 pg/mL vs. 44 ± 26 pg/mL). In contrast, lighting conditions including blue components reduced melatonin increase significantly both during (office daylight white: 25 ± 16 pg/mL, bathroom daylight white: 24 ± 10 pg/mL, Planon warm white: 26 ± 14 pg/mL, hall daylight white: 22 ± 14 pg/mL) and after light exposure (office daylight white: 25 ± 15 pg/mL, bathroom daylight white: 23 ± 9 pg/mL, Planon warm white: 24 ± 13 pg/mL, hall daylight white: 22 ± 26 pg/mL). Subjective alertness was significantly increased after exposure to three of the lighting conditions which included blue spectral components in their spectra. Evening exposure to conventional lamps in an everyday setting influences melatonin excretion and alertness perception within 30 min.</description><subject>Alzheimer's disease</subject><subject>Circadian rhythm</subject><subject>Electronic mail systems</subject><subject>Gene expression</subject><subject>Influence</subject><subject>Insomnia</subject><subject>Melatonin</subject><subject>Mental depression</subject><subject>Mental disorders</subject><subject>Physiology</subject><subject>Sleep</subject><issn>1422-0067</issn><issn>1661-6596</issn><issn>1422-0067</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkU1vFDEMhkcIREvhxhlF4tIDU5yvnQmHSqjio1KlXuAcZbLenawyyZBkKvgV_ctk6VItnGzZj1_ZfpvmNYULzhW8d7spUwGMyY4_aU6pYKwFWHVPj_KT5kXOOwDGmVTPmxPGueyZ6E-b-9ulkLghZUTizUBMWBMXSvxTGEwZU4zTB4J3GFzYkjzGVNqCaSL4c455SUgqbGOoQHExGE-8246F5GWeE-aMmUzoTYl1_qBuE5p93XhMJVSGzJgszvv5l82zjfEZXx3iWfP986dvV1_bm9sv11cfb1orKCutsWtOpVUGkSvJ6NAJ6NlgQKz4xq57sQKJYBUIhaIiQlJJEYa-A6ooID9rLh9052WYcG3r9sl4PSc3mfRLR-P0v53gRr2Nd7o-rgfgVeD8IJDijwVz0ZPLFr03AeOSNWU967nqhKzo2__QXVxSfVWlJFtBdU51lXr3QNkUc064eVyGgt47rY-drvib4wMe4b_W8t_rZ6e3</recordid><startdate>20130128</startdate><enddate>20130128</enddate><creator>Wahnschaffe, Amely</creator><creator>Haedel, Sven</creator><creator>Rodenbeck, Andrea</creator><creator>Stoll, Claudia</creator><creator>Rudolph, Horst</creator><creator>Kozakov, Ruslan</creator><creator>Schoepp, Heinz</creator><creator>Kunz, Dieter</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130128</creationdate><title>Out of the lab and into the bathroom: evening short-term exposure to conventional light suppresses melatonin and increases alertness perception</title><author>Wahnschaffe, Amely ; Haedel, Sven ; Rodenbeck, Andrea ; Stoll, Claudia ; Rudolph, Horst ; Kozakov, Ruslan ; Schoepp, Heinz ; Kunz, Dieter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c412t-acd315c9aee39521b74082ba0463fcd84605e0c9049e4e3945151e0b8701910e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Alzheimer's disease</topic><topic>Circadian rhythm</topic><topic>Electronic mail systems</topic><topic>Gene expression</topic><topic>Influence</topic><topic>Insomnia</topic><topic>Melatonin</topic><topic>Mental depression</topic><topic>Mental disorders</topic><topic>Physiology</topic><topic>Sleep</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wahnschaffe, Amely</creatorcontrib><creatorcontrib>Haedel, Sven</creatorcontrib><creatorcontrib>Rodenbeck, Andrea</creatorcontrib><creatorcontrib>Stoll, Claudia</creatorcontrib><creatorcontrib>Rudolph, Horst</creatorcontrib><creatorcontrib>Kozakov, Ruslan</creatorcontrib><creatorcontrib>Schoepp, Heinz</creatorcontrib><creatorcontrib>Kunz, Dieter</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of molecular sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wahnschaffe, Amely</au><au>Haedel, Sven</au><au>Rodenbeck, Andrea</au><au>Stoll, Claudia</au><au>Rudolph, Horst</au><au>Kozakov, Ruslan</au><au>Schoepp, Heinz</au><au>Kunz, Dieter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Out of the lab and into the bathroom: evening short-term exposure to conventional light suppresses melatonin and increases alertness perception</atitle><jtitle>International journal of molecular sciences</jtitle><addtitle>Int J Mol Sci</addtitle><date>2013-01-28</date><risdate>2013</risdate><volume>14</volume><issue>2</issue><spage>2573</spage><epage>2589</epage><pages>2573-2589</pages><issn>1422-0067</issn><issn>1661-6596</issn><eissn>1422-0067</eissn><abstract>Life in 24-h society relies on the use of artificial light at night that might disrupt synchronization of the endogenous circadian timing system to the solar day. This could have a negative impact on sleep-wake patterns and psychiatric symptoms. The aim of the study was to investigate the influence of evening light emitted by domestic and work place lamps in a naturalistic setting on melatonin levels and alertness in humans. Healthy subjects (6 male, 3 female, 22-33 years) were exposed to constant dim light (<10 lx) for six evenings from 7:00 p.m. to midnight. On evenings 2 through 6, 1 h before habitual bedtime, they were also exposed to light emitted by 5 different conventional lamps for 30 min. Exposure to yellow light did not alter the increase of melatonin in saliva compared to dim light baseline during (38 ± 27 pg/mL vs. 39 ± 23 pg/mL) and after light exposure (39 ± 22 pg/mL vs. 44 ± 26 pg/mL). In contrast, lighting conditions including blue components reduced melatonin increase significantly both during (office daylight white: 25 ± 16 pg/mL, bathroom daylight white: 24 ± 10 pg/mL, Planon warm white: 26 ± 14 pg/mL, hall daylight white: 22 ± 14 pg/mL) and after light exposure (office daylight white: 25 ± 15 pg/mL, bathroom daylight white: 23 ± 9 pg/mL, Planon warm white: 24 ± 13 pg/mL, hall daylight white: 22 ± 26 pg/mL). Subjective alertness was significantly increased after exposure to three of the lighting conditions which included blue spectral components in their spectra. Evening exposure to conventional lamps in an everyday setting influences melatonin excretion and alertness perception within 30 min.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>23358248</pmid><doi>10.3390/ijms14022573</doi><tpages>17</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1422-0067 |
| ispartof | International journal of molecular sciences, 2013-01, Vol.14 (2), p.2573-2589 |
| issn | 1422-0067 1661-6596 1422-0067 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3588003 |
| source | MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Alzheimer's disease Circadian rhythm Electronic mail systems Gene expression Influence Insomnia Melatonin Mental depression Mental disorders Physiology Sleep |
| title | Out of the lab and into the bathroom: evening short-term exposure to conventional light suppresses melatonin and increases alertness perception |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T00%3A31%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Out%20of%20the%20lab%20and%20into%20the%20bathroom:%20evening%20short-term%20exposure%20to%20conventional%20light%20suppresses%20melatonin%20and%20increases%20alertness%20perception&rft.jtitle=International%20journal%20of%20molecular%20sciences&rft.au=Wahnschaffe,%20Amely&rft.date=2013-01-28&rft.volume=14&rft.issue=2&rft.spage=2573&rft.epage=2589&rft.pages=2573-2589&rft.issn=1422-0067&rft.eissn=1422-0067&rft_id=info:doi/10.3390/ijms14022573&rft_dat=%3Cproquest_pubme%3E1282839745%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1526025797&rft_id=info:pmid/23358248&rfr_iscdi=true |