Effects of an Engineered Anti-HER2 Antibody chA21 on Invasion of Human Ovarian Carcinoma Cell In Vitro

Objective： HER-2 plays an important role in the development and progression of ovarian carcinoma. A number of monoclonal antibodies （MAbs） and engineered antibody fragments （such as scFvs） against the subdomain II or IV of HER-2 extracellular domain （ECD） have been developed. We investigated the eff...

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Veröffentlicht in:	Chinese journal of cancer research 2011-06, Vol.23 (2), p.147-152
Hauptverfasser:	Gao, Yi, Wu, Qiang, Wu, Zheng-sheng, Zhang, Gui-hong, Zhang, An-li
Format:	Artikel
Sprache:	eng
Schlagworte:	Medicine Medicine & Public Health Original Original Article p38MAPK 体外 侵袭 单克隆抗体 卵巢癌 基质金属蛋白酶-2 肿瘤细胞 设计
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