Development of a Generic Microfluidic Device for Simultaneous Detection of Antibodies and Nucleic Acids in Oral Fluids

A prototype dual-path microfluidic device (Rheonix CARD) capable of performing simultaneously screening (antigen or antibody) and confirmatory (nucleic acid) detection of pathogens is described. The device fully integrates sample processing, antigen or antibody detection, and nucleic acid amplificat...

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Veröffentlicht in:	BioMed research international 2013-01, Vol.2013 (2013), p.1-12
Hauptverfasser:	Corstjens, Paul L. A. M., Malamud, Daniel, Niedbala, R. Sam, Tanke, Hans J., González, Jesús M., de Dood, Claudia J., Geva, Eran, Abrams, William R., Chen, Zongyuan, Zhou, Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Antibodies Antibodies - analysis Antibodies - chemistry Antibodies, Viral - analysis Diagnostic equipment (Medical) Equipment Design HIV HIV Infections - diagnosis Human immunodeficiency virus Humans Infections Microfluidic Analytical Techniques - instrumentation Microfluidics Nucleic acids Nucleic Acids - analysis Phosphorus - chemistry Physiological aspects Polymerase Chain Reaction RNA, Viral - analysis Saliva - metabolism Technological change Tuberculosis Viral antibodies Viral infections
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