Possible association of decreased NKG2D expression levels and suppression of the activity of natural killer cells in patients with colorectal cancer

Natural-killer group 2 (NKG2), a natural killer (NK) cell receptor, plays a critical role in regulating NK cytotoxicity. In this study, we investigated the expression levels of natural killer group 2 member A (NKG2A) and natural killer group 2 member D (NKG2D) in NK cells as well as the regulatory f...

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Veröffentlicht in:	International journal of oncology 2012-04, Vol.40 (4), p.1285-1290
Hauptverfasser:	SHEN, YAJUAN, LU, CHAO, TIAN, WENJUN, WANG, LAICHENG, CUI, BIN, JIAO, YULIAN, MA, CHUNYAN, JU, YING, ZHU, LING, SHAO, CHUNHONG, LIU, XINQI, WANG, JIAN, ZHANG, BINGCHANG, LU, ZHIMING
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Case-Control Studies Cell Line, Tumor colorectal cancer Colorectal Neoplasms - immunology Colorectal Neoplasms - metabolism Female Gastroenterology. Liver. Pancreas. Abdomen HT29 Cells Humans Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Male Medical sciences Middle Aged natural killer cells NK Cell Lectin-Like Receptor Subfamily K - biosynthesis NK Cell Lectin-Like Receptor Subfamily K - deficiency NK Cell Lectin-Like Receptor Subfamily K - immunology NKG2 Stomach. Duodenum. Small intestine. Colon. Rectum. Anus suppression Tumors
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