Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer’s Disease

Alzheimer’s disease (AD) is associated with a cascade of pathological events involving formation of amyloid-based neuritic plaques and tau-based neurofibrillary tangles, changes in brain structure and function, and eventually, cognitive impairment and functional disability. The precise sequence of w...

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Veröffentlicht in:	Brain imaging and behavior 2012-12, Vol.6 (4), p.610-620
Hauptverfasser:	Han, S. Duke, Gruhl, Jonathan, Beckett, Laurel, Dodge, Hiroko H., Stricker, Nikki H., Farias, Sarah, Mungas, Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	ADNI: Friday Harbor 2011 Workshop SPECIAL ISSUE Aged Aged, 80 and over Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - diagnosis Alzheimer's disease Amyloid beta-Peptides - cerebrospinal fluid Biomarkers Biomarkers - blood Biomedical and Life Sciences Biomedicine Cognition & reasoning Diagnosis, Computer-Assisted - methods Female Humans Male Medical imaging Middle Aged Neuroimaging Neuropsychological Tests Neuropsychology Neuroradiology Neurosciences Proportional Hazards Models Psychiatry Reproducibility of Results Sensitivity and Specificity tau Proteins - cerebrospinal fluid
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