Antiulcer Activity of Indigenous Plant Operculina turpethum Linn.
In the Indian traditional system of medicine Operculina turpethum is commonly used to treat various ailments including peptic ulcer, inflammation, and pain. Ulcer preventive and ulcer protective activities of HAOP and MOP stem bark extracts of Operculina turpethum (100 mg/kg, b.w., orally) were eval...
Gespeichert in:
| Veröffentlicht in: | Evidence-based complementary and alternative medicine 2013-01, Vol.2013 (2013), p.1-7 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 7 |
|---|---|
| container_issue | 2013 |
| container_start_page | 1 |
| container_title | Evidence-based complementary and alternative medicine |
| container_volume | 2013 |
| creator | Ignatius, Vidya Narayanan, Madhusudhanan Subramanian, Venkataraman Periyasamy, Balasubramanian Maruthaiveeran |
| description | In the Indian traditional system of medicine Operculina turpethum is commonly used to treat various ailments including peptic ulcer, inflammation, and pain. Ulcer preventive and ulcer protective activities of HAOP and MOP stem bark extracts of Operculina turpethum (100 mg/kg, b.w., orally) were evaluated employing aspirin + pylorus ligation (APL) model in experimental rats. The results suggested that both extracts (HAOP and MOP) possess enhanced ulcer preventive and protective activities when compared with the standard drug ranitidine. HAOP showed more pronounced effect when compared to MOP. Further the result of the histopathological and biochemical studies also confirms potent ulcer preventive and protective nature of a extracts in a similar manner. |
| doi_str_mv | 10.1155/2013/272134 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3582069</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1316054519</sourcerecordid><originalsourceid>FETCH-LOGICAL-c429t-984f28dd5c6fe7a90abe4b6a659688716f0d6c78ca584bb65c0148024d7a70f3</originalsourceid><addsrcrecordid>eNqF0c1LwzAYBvAgitPpybNS8CLKZr6TXoQx_IKBHnbwFtI03TK6dKbpZP-9HdWhXjzlhfx4eF8eAM4QHCLE2C2GiNxigRGhe-AICYoGFEu5v5vFWw8c1_UCQpwKIQ5BDxMqOJfkCIxGPrqmNDYkIxPd2sVNUhXJs8_dzPqqqZPXUvuYvKxsME3pvE5iE1Y2zptlMnHeD0_AQaHL2p5-vX0wfbifjp8Gk5fH5_FoMjAUp3GQSlpgmefM8MIKnUKdWZpxzVnKpRSIFzDnRkijmaRZxpmBiEqIaS60gAXpg7sudtVkS5sb62PQpVoFt9Rhoyrt1O8f7-ZqVq0VYRJDnrYBV18BoXpvbB3V0tXGlu15tr1TIYI4ZJShLb38QxdVE3x7nUICQUGoTGmrbjplQlXXwRa7ZRBU22bUthnVNdPqi5_77-x3FS247sDc-Vx_uH_SzjtsW2ILvcOUpZgT8gmdOZ76</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1710734894</pqid></control><display><type>article</type><title>Antiulcer Activity of Indigenous Plant Operculina turpethum Linn.</title><source>PubMed Central Open Access</source><source>Wiley Online Library Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Ignatius, Vidya ; Narayanan, Madhusudhanan ; Subramanian, Venkataraman ; Periyasamy, Balasubramanian Maruthaiveeran</creator><contributor>Ríos, José Luis ; José Luis Ríos</contributor><creatorcontrib>Ignatius, Vidya ; Narayanan, Madhusudhanan ; Subramanian, Venkataraman ; Periyasamy, Balasubramanian Maruthaiveeran ; Ríos, José Luis ; José Luis Ríos</creatorcontrib><description>In the Indian traditional system of medicine Operculina turpethum is commonly used to treat various ailments including peptic ulcer, inflammation, and pain. Ulcer preventive and ulcer protective activities of HAOP and MOP stem bark extracts of Operculina turpethum (100 mg/kg, b.w., orally) were evaluated employing aspirin + pylorus ligation (APL) model in experimental rats. The results suggested that both extracts (HAOP and MOP) possess enhanced ulcer preventive and protective activities when compared with the standard drug ranitidine. HAOP showed more pronounced effect when compared to MOP. Further the result of the histopathological and biochemical studies also confirms potent ulcer preventive and protective nature of a extracts in a similar manner.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2013/272134</identifier><identifier>PMID: 23476683</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Puplishing Corporation</publisher><subject>Acids ; Albinism ; Animals ; Aspirin ; Bark ; Drugs ; Indigenous plants ; Medical research ; Medicinal plants ; Medicine ; Operculina turpethum ; Pain ; Pharmaceuticals ; Physiology ; Ranitidine ; Science ; Toxicology ; Traditional medicine ; Ulcers</subject><ispartof>Evidence-based complementary and alternative medicine, 2013-01, Vol.2013 (2013), p.1-7</ispartof><rights>Copyright © 2013 Vidya Ignatius et al.</rights><rights>Copyright © 2013 Vidya Ignatius et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2013 Vidya Ignatius et al. 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c429t-984f28dd5c6fe7a90abe4b6a659688716f0d6c78ca584bb65c0148024d7a70f3</citedby><cites>FETCH-LOGICAL-c429t-984f28dd5c6fe7a90abe4b6a659688716f0d6c78ca584bb65c0148024d7a70f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582069/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582069/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23476683$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Ríos, José Luis</contributor><contributor>José Luis Ríos</contributor><creatorcontrib>Ignatius, Vidya</creatorcontrib><creatorcontrib>Narayanan, Madhusudhanan</creatorcontrib><creatorcontrib>Subramanian, Venkataraman</creatorcontrib><creatorcontrib>Periyasamy, Balasubramanian Maruthaiveeran</creatorcontrib><title>Antiulcer Activity of Indigenous Plant Operculina turpethum Linn.</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>In the Indian traditional system of medicine Operculina turpethum is commonly used to treat various ailments including peptic ulcer, inflammation, and pain. Ulcer preventive and ulcer protective activities of HAOP and MOP stem bark extracts of Operculina turpethum (100 mg/kg, b.w., orally) were evaluated employing aspirin + pylorus ligation (APL) model in experimental rats. The results suggested that both extracts (HAOP and MOP) possess enhanced ulcer preventive and protective activities when compared with the standard drug ranitidine. HAOP showed more pronounced effect when compared to MOP. Further the result of the histopathological and biochemical studies also confirms potent ulcer preventive and protective nature of a extracts in a similar manner.</description><subject>Acids</subject><subject>Albinism</subject><subject>Animals</subject><subject>Aspirin</subject><subject>Bark</subject><subject>Drugs</subject><subject>Indigenous plants</subject><subject>Medical research</subject><subject>Medicinal plants</subject><subject>Medicine</subject><subject>Operculina turpethum</subject><subject>Pain</subject><subject>Pharmaceuticals</subject><subject>Physiology</subject><subject>Ranitidine</subject><subject>Science</subject><subject>Toxicology</subject><subject>Traditional medicine</subject><subject>Ulcers</subject><issn>1741-427X</issn><issn>1741-4288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0c1LwzAYBvAgitPpybNS8CLKZr6TXoQx_IKBHnbwFtI03TK6dKbpZP-9HdWhXjzlhfx4eF8eAM4QHCLE2C2GiNxigRGhe-AICYoGFEu5v5vFWw8c1_UCQpwKIQ5BDxMqOJfkCIxGPrqmNDYkIxPd2sVNUhXJs8_dzPqqqZPXUvuYvKxsME3pvE5iE1Y2zptlMnHeD0_AQaHL2p5-vX0wfbifjp8Gk5fH5_FoMjAUp3GQSlpgmefM8MIKnUKdWZpxzVnKpRSIFzDnRkijmaRZxpmBiEqIaS60gAXpg7sudtVkS5sb62PQpVoFt9Rhoyrt1O8f7-ZqVq0VYRJDnrYBV18BoXpvbB3V0tXGlu15tr1TIYI4ZJShLb38QxdVE3x7nUICQUGoTGmrbjplQlXXwRa7ZRBU22bUthnVNdPqi5_77-x3FS247sDc-Vx_uH_SzjtsW2ILvcOUpZgT8gmdOZ76</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Ignatius, Vidya</creator><creator>Narayanan, Madhusudhanan</creator><creator>Subramanian, Venkataraman</creator><creator>Periyasamy, Balasubramanian Maruthaiveeran</creator><general>Hindawi Puplishing Corporation</general><general>Hindawi Publishing Corporation</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130101</creationdate><title>Antiulcer Activity of Indigenous Plant Operculina turpethum Linn.</title><author>Ignatius, Vidya ; Narayanan, Madhusudhanan ; Subramanian, Venkataraman ; Periyasamy, Balasubramanian Maruthaiveeran</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c429t-984f28dd5c6fe7a90abe4b6a659688716f0d6c78ca584bb65c0148024d7a70f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acids</topic><topic>Albinism</topic><topic>Animals</topic><topic>Aspirin</topic><topic>Bark</topic><topic>Drugs</topic><topic>Indigenous plants</topic><topic>Medical research</topic><topic>Medicinal plants</topic><topic>Medicine</topic><topic>Operculina turpethum</topic><topic>Pain</topic><topic>Pharmaceuticals</topic><topic>Physiology</topic><topic>Ranitidine</topic><topic>Science</topic><topic>Toxicology</topic><topic>Traditional medicine</topic><topic>Ulcers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ignatius, Vidya</creatorcontrib><creatorcontrib>Narayanan, Madhusudhanan</creatorcontrib><creatorcontrib>Subramanian, Venkataraman</creatorcontrib><creatorcontrib>Periyasamy, Balasubramanian Maruthaiveeran</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Evidence-based complementary and alternative medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ignatius, Vidya</au><au>Narayanan, Madhusudhanan</au><au>Subramanian, Venkataraman</au><au>Periyasamy, Balasubramanian Maruthaiveeran</au><au>Ríos, José Luis</au><au>José Luis Ríos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antiulcer Activity of Indigenous Plant Operculina turpethum Linn.</atitle><jtitle>Evidence-based complementary and alternative medicine</jtitle><addtitle>Evid Based Complement Alternat Med</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>2013</volume><issue>2013</issue><spage>1</spage><epage>7</epage><pages>1-7</pages><issn>1741-427X</issn><eissn>1741-4288</eissn><abstract>In the Indian traditional system of medicine Operculina turpethum is commonly used to treat various ailments including peptic ulcer, inflammation, and pain. Ulcer preventive and ulcer protective activities of HAOP and MOP stem bark extracts of Operculina turpethum (100 mg/kg, b.w., orally) were evaluated employing aspirin + pylorus ligation (APL) model in experimental rats. The results suggested that both extracts (HAOP and MOP) possess enhanced ulcer preventive and protective activities when compared with the standard drug ranitidine. HAOP showed more pronounced effect when compared to MOP. Further the result of the histopathological and biochemical studies also confirms potent ulcer preventive and protective nature of a extracts in a similar manner.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Puplishing Corporation</pub><pmid>23476683</pmid><doi>10.1155/2013/272134</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1741-427X |
| ispartof | Evidence-based complementary and alternative medicine, 2013-01, Vol.2013 (2013), p.1-7 |
| issn | 1741-427X 1741-4288 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3582069 |
| source | PubMed Central Open Access; Wiley Online Library Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Acids Albinism Animals Aspirin Bark Drugs Indigenous plants Medical research Medicinal plants Medicine Operculina turpethum Pain Pharmaceuticals Physiology Ranitidine Science Toxicology Traditional medicine Ulcers |
| title | Antiulcer Activity of Indigenous Plant Operculina turpethum Linn. |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T11%3A30%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antiulcer%20Activity%20of%20Indigenous%20Plant%20Operculina%20turpethum%20Linn.&rft.jtitle=Evidence-based%20complementary%20and%20alternative%20medicine&rft.au=Ignatius,%20Vidya&rft.date=2013-01-01&rft.volume=2013&rft.issue=2013&rft.spage=1&rft.epage=7&rft.pages=1-7&rft.issn=1741-427X&rft.eissn=1741-4288&rft_id=info:doi/10.1155/2013/272134&rft_dat=%3Cproquest_pubme%3E1316054519%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1710734894&rft_id=info:pmid/23476683&rfr_iscdi=true |