Specific Conserved C-terminal Amino Acids of Caenorhabditis elegans HMP-1/α-Catenin Modulate F-actin Binding Independently of Vinculin

Stable intercellular adhesions formed through the cadherin-catenin complex are important determinants of proper tissue architecture and help maintain tissue integrity during morphogenetic movements in developing embryos. A key regulator of this stability is α-catenin, which connects the cadherin-cat...

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Veröffentlicht in:The Journal of biological chemistry 2013-02, Vol.288 (8), p.5694-5706
Hauptverfasser: Maiden, Stephanie L., Harrison, Neale, Keegan, Jack, Cain, Brian, Lynch, Allison M., Pettitt, Jonathan, Hardin, Jeff
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Sprache:eng
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