Effects of Chronic and Acute Oestrogen Replacement Therapy in Aged Animals after Experimental Stroke

The effect of oestrogen replacement therapy (ERT) on stroke incidence and severity has been extensively debated. Clinical trials of ERT have demonstrated an increased risk of stroke in treated women, although the study participants were well past menopause when therapy was initiated. It has been sug...

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Veröffentlicht in:	Journal of neuroendocrinology 2012-02, Vol.24 (2), p.319-330
Hauptverfasser:	Liu, F., Benashski, S. E., Xu, Y., Siegel, M., McCullough, L. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors ageing Aging - drug effects Aging - physiology Animals Biological and medical sciences Disease Models, Animal Drug Administration Schedule Estradiol - administration & dosage Estradiol - pharmacology Estrogen Replacement Therapy - adverse effects Estrogen Replacement Therapy - methods Female Fundamental and applied biological sciences. Psychology inflammation Male Medical sciences Mice Mice, Inbred C57BL Neurology Neuroprotective Agents - administration & dosage Neuroprotective Agents - pharmacology NF-κB oestrogen sex differences Stroke - physiopathology Stroke - psychology Stroke Rehabilitation Time Factors Vascular diseases and vascular malformations of the nervous system Vertebrates: endocrinology
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