Intramolecular Proton Transfer in Channelrhodopsins

Channelrhodopsins serve as photoreceptors that control the motility behavior of green flagellate algae and act as light-gated ion channels when heterologously expressed in animal cells. Here, we report direct measurements of proton transfer from the retinylidene Schiff base in several channelrhodops...

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Veröffentlicht in:	Biophysical journal 2013-02, Vol.104 (4), p.807-817
Hauptverfasser:	Sineshchekov, Oleg A., Govorunova, Elena G., Wang, Jihong, Li, Hai, Spudich, John L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algae Archaea - chemistry Aspartic Acid - chemistry Aspartic Acid - genetics Atoms & subatomic particles Biophysics Channels and Transporters Chlorophyta - chemistry Glutamic Acid - chemistry Glutamic Acid - genetics HEK293 Cells Humans Ion Channel Gating - genetics Ion Transport Light Membrane Potentials - genetics Motility Mutation Proteins Protons Retinoids - chemistry Retinoids - metabolism Rhodopsins, Microbial - chemistry Rhodopsins, Microbial - genetics Rhodopsins, Microbial - metabolism
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