Dopamine D1 receptors within the basolateral amygdala mediate heroin-induced conditioned immunomodulation

Abstract This study investigates the role of basolateral amygdala (BLA) dopamine in heroin-induced conditioned immunomodulation. Animals underwent conditioning in which heroin administration was repeatedly paired with placement into a conditioning chamber. Six days after the final conditioning sessi...

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Veröffentlicht in:	Journal of neuroimmunology 2010-09, Vol.226 (1), p.38-47
Hauptverfasser:	Szczytkowski, Jennifer L, Lysle, Donald T
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Amygdala Amygdala - drug effects Amygdala - metabolism Analysis of Variance Animals Benzazepines - pharmacology Conditioning, Operant - drug effects Conditioning, Operant - physiology Dopamine Antagonists - pharmacology Drug Interactions Enzyme-Linked Immunosorbent Assay - methods Gene Expression Regulation - drug effects Heroin - pharmacology Interleukin-1beta - metabolism Lipopolysaccharides - pharmacology Male Microinjections - methods Narcotics - pharmacology Neurology Nitrates - blood Nitric Oxide Synthase Type II - genetics Nitric Oxide Synthase Type II - metabolism Nitrites - blood Rats Rats, Inbred Lew Receptors, Dopamine D1 - metabolism RNA, Messenger - metabolism Tumor Necrosis Factor-alpha - metabolism
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