Central Serous Chorioretinopathy: Update on Pathophysiology and Treatment
Abstract Recent technological advances—new pathophysiological insights, new imaging techniques for diagnosis and management, and new treatments—have led to an improved understanding of central serous chorioretinopathy (CSC). The primary role of the choroid has become more widely accepted with widesp...
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| Veröffentlicht in: | Survey of ophthalmology 2013-03, Vol.58 (2), p.103-126 |
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| container_title | Survey of ophthalmology |
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| creator | Nicholson, Benjamin, MD Noble, Jason, MD Forooghian, Farzin, MD Meyerle, Catherine, MD |
| description | Abstract Recent technological advances—new pathophysiological insights, new imaging techniques for diagnosis and management, and new treatments—have led to an improved understanding of central serous chorioretinopathy (CSC). The primary role of the choroid has become more widely accepted with widespread use of indocyanine green angiography. Optical coherence tomography (OCT), and particularly enhanced depth imaging OCT, demonstrate a thickened and engorged choroid. Adaptive optics, fundus autofluorescence, multifocal electroretinography, microperimetry, and contrast sensitivity testing reveal that patients with even a mild course suffer previously undetected anatomic and functional loss. Although focal laser and photodynamic therapy are the current standard of care for persistent subretinal fluid in CSC, they are not appropriate in all cases, and the optimal timing of intervention remains unclear. |
| doi_str_mv | 10.1016/j.survophthal.2012.07.004 |
| format | Article |
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The primary role of the choroid has become more widely accepted with widespread use of indocyanine green angiography. Optical coherence tomography (OCT), and particularly enhanced depth imaging OCT, demonstrate a thickened and engorged choroid. Adaptive optics, fundus autofluorescence, multifocal electroretinography, microperimetry, and contrast sensitivity testing reveal that patients with even a mild course suffer previously undetected anatomic and functional loss. Although focal laser and photodynamic therapy are the current standard of care for persistent subretinal fluid in CSC, they are not appropriate in all cases, and the optimal timing of intervention remains unclear.</description><identifier>ISSN: 0039-6257</identifier><identifier>EISSN: 1879-3304</identifier><identifier>DOI: 10.1016/j.survophthal.2012.07.004</identifier><identifier>PMID: 23410821</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>central serous chorioretinopathy ; Central Serous Chorioretinopathy - diagnosis ; Central Serous Chorioretinopathy - physiopathology ; Central Serous Chorioretinopathy - therapy ; Coloring Agents ; corticosteroids ; diffuse retinal pigment epitheliopathy ; Fluorescein Angiography ; fundus autofluorescence ; Humans ; Indocyanine Green ; indocyanine green angiography ; Laser Coagulation ; Ophthalmology ; optical coherence tomography ; Photochemotherapy ; photodynamic therapy ; Tomography, Optical Coherence ; Visual Field Tests</subject><ispartof>Survey of ophthalmology, 2013-03, Vol.58 (2), p.103-126</ispartof><rights>2013</rights><rights>Published by Elsevier Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c604t-c507ddde7d227ce59e0a3def8a2471a7eb282148e35acb56356b6d918e6a9d963</citedby><cites>FETCH-LOGICAL-c604t-c507ddde7d227ce59e0a3def8a2471a7eb282148e35acb56356b6d918e6a9d963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.survophthal.2012.07.004$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,777,781,882,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23410821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nicholson, Benjamin, MD</creatorcontrib><creatorcontrib>Noble, Jason, MD</creatorcontrib><creatorcontrib>Forooghian, Farzin, MD</creatorcontrib><creatorcontrib>Meyerle, Catherine, MD</creatorcontrib><title>Central Serous Chorioretinopathy: Update on Pathophysiology and Treatment</title><title>Survey of ophthalmology</title><addtitle>Surv Ophthalmol</addtitle><description>Abstract Recent technological advances—new pathophysiological insights, new imaging techniques for diagnosis and management, and new treatments—have led to an improved understanding of central serous chorioretinopathy (CSC). The primary role of the choroid has become more widely accepted with widespread use of indocyanine green angiography. Optical coherence tomography (OCT), and particularly enhanced depth imaging OCT, demonstrate a thickened and engorged choroid. Adaptive optics, fundus autofluorescence, multifocal electroretinography, microperimetry, and contrast sensitivity testing reveal that patients with even a mild course suffer previously undetected anatomic and functional loss. Although focal laser and photodynamic therapy are the current standard of care for persistent subretinal fluid in CSC, they are not appropriate in all cases, and the optimal timing of intervention remains unclear.</description><subject>central serous chorioretinopathy</subject><subject>Central Serous Chorioretinopathy - diagnosis</subject><subject>Central Serous Chorioretinopathy - physiopathology</subject><subject>Central Serous Chorioretinopathy - therapy</subject><subject>Coloring Agents</subject><subject>corticosteroids</subject><subject>diffuse retinal pigment epitheliopathy</subject><subject>Fluorescein Angiography</subject><subject>fundus autofluorescence</subject><subject>Humans</subject><subject>Indocyanine Green</subject><subject>indocyanine green angiography</subject><subject>Laser Coagulation</subject><subject>Ophthalmology</subject><subject>optical coherence tomography</subject><subject>Photochemotherapy</subject><subject>photodynamic therapy</subject><subject>Tomography, Optical Coherence</subject><subject>Visual Field Tests</subject><issn>0039-6257</issn><issn>1879-3304</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUsFq3DAUFKWh2W77C8W99WLnSbItu4dAMWkbCCSQ5Cy00ttYW6_lSvaC_75yNwlpTzkJnubNDDOPkM8UMgq0PNtlYfIHN7Rjq7qMAWUZiAwgf0NWtBJ1yjnkb8kKgNdpyQpxSt6HsIOI4LV4R04ZzylUjK7IZYP96FWX3KJ3U0ia1nnrPI62d4Ma2_lrcj8YNWLi-uQmDqLqHKzr3MOcqN4kdx7VuI8kH8jJVnUBPz6-a3L__eKu-ZleXf-4bL5dpbqEfEx1AcIYg8IwJjQWNYLiBreVYrmgSuCGRWN5hbxQelOUvCg3palphaWqTV3yNTk_8g7TZo9GH_3Lwdu98rN0ysp_f3rbygd3kLwQOftL8OWRwLvfE4ZR7m3Q2HWqxxiBpKyqONQVX6D1Eaq9C8Hj9lmGglyqkDv5ogq5VCFByCXoNfn00ufz5lP2EdAcARjTOlj0MmiLvUZjPepRGmdfJXP-H4vubG-16n7hjGHnJt_HOiSVIe7I2-UmlpOgDIAKVvA_y2y4Tw</recordid><startdate>20130301</startdate><enddate>20130301</enddate><creator>Nicholson, Benjamin, MD</creator><creator>Noble, Jason, MD</creator><creator>Forooghian, Farzin, MD</creator><creator>Meyerle, Catherine, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130301</creationdate><title>Central Serous Chorioretinopathy: Update on Pathophysiology and Treatment</title><author>Nicholson, Benjamin, MD ; Noble, Jason, MD ; Forooghian, Farzin, MD ; Meyerle, Catherine, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c604t-c507ddde7d227ce59e0a3def8a2471a7eb282148e35acb56356b6d918e6a9d963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>central serous chorioretinopathy</topic><topic>Central Serous Chorioretinopathy - diagnosis</topic><topic>Central Serous Chorioretinopathy - physiopathology</topic><topic>Central Serous Chorioretinopathy - therapy</topic><topic>Coloring Agents</topic><topic>corticosteroids</topic><topic>diffuse retinal pigment epitheliopathy</topic><topic>Fluorescein Angiography</topic><topic>fundus autofluorescence</topic><topic>Humans</topic><topic>Indocyanine Green</topic><topic>indocyanine green angiography</topic><topic>Laser Coagulation</topic><topic>Ophthalmology</topic><topic>optical coherence tomography</topic><topic>Photochemotherapy</topic><topic>photodynamic therapy</topic><topic>Tomography, Optical Coherence</topic><topic>Visual Field Tests</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nicholson, Benjamin, MD</creatorcontrib><creatorcontrib>Noble, Jason, MD</creatorcontrib><creatorcontrib>Forooghian, Farzin, MD</creatorcontrib><creatorcontrib>Meyerle, Catherine, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Survey of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nicholson, Benjamin, MD</au><au>Noble, Jason, MD</au><au>Forooghian, Farzin, MD</au><au>Meyerle, Catherine, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central Serous Chorioretinopathy: Update on Pathophysiology and Treatment</atitle><jtitle>Survey of ophthalmology</jtitle><addtitle>Surv Ophthalmol</addtitle><date>2013-03-01</date><risdate>2013</risdate><volume>58</volume><issue>2</issue><spage>103</spage><epage>126</epage><pages>103-126</pages><issn>0039-6257</issn><eissn>1879-3304</eissn><abstract>Abstract Recent technological advances—new pathophysiological insights, new imaging techniques for diagnosis and management, and new treatments—have led to an improved understanding of central serous chorioretinopathy (CSC). 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| ispartof | Survey of ophthalmology, 2013-03, Vol.58 (2), p.103-126 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | central serous chorioretinopathy Central Serous Chorioretinopathy - diagnosis Central Serous Chorioretinopathy - physiopathology Central Serous Chorioretinopathy - therapy Coloring Agents corticosteroids diffuse retinal pigment epitheliopathy Fluorescein Angiography fundus autofluorescence Humans Indocyanine Green indocyanine green angiography Laser Coagulation Ophthalmology optical coherence tomography Photochemotherapy photodynamic therapy Tomography, Optical Coherence Visual Field Tests |
| title | Central Serous Chorioretinopathy: Update on Pathophysiology and Treatment |
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