Site-specific S-nitrosylation of Integrin α6 Increases Prostate Cancer Cell Migration by Increasing Integrin β1 Association and Reducing Adherence to Laminin-1

The increased mortality in prostate cancer is usually the result of metastatic progression of the disease from the organ-confined location. Among the major events in this progression cascade are increased cell migration and loss of adhesion. Moreover, elevated levels of nitric oxide (NO) and inducib...

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Veröffentlicht in:Biochemistry (Easton) 2012-11, Vol.51 (48), p.9689-9697
Hauptverfasser: Isaac, Jared, Tarapore, Pheruza, Zhang, Xiang, Lam, Ying-Wai, Ho, Shuk-Mei
Format: Artikel
Sprache:eng
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