Interleukin-10: An Anti-Inflammatory Marker To Target Atherosclerotic Lesions via PEGylated Liposomes

Atherosclerosis (AS) causes cardiovascular disease, which leads to fatal clinical end points like myocardial infarction or stroke, the most prevalent causes of death in developed countries. An early, noninvasive method of detection and diagnosis of atherosclerotic lesions is necessary to prevent and...

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Veröffentlicht in:	Molecular pharmaceutics 2013-01, Vol.10 (1), p.175-186
Hauptverfasser:	Almer, Gunter, Frascione, Daniela, Pali-Schöll, Isabella, Vonach, Caroline, Lukschal, Anna, Stremnitzer, Caroline, Diesner, Susanne C, Jensen-Jarolim, Erika, Prassl, Ruth, Mangge, Harald
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - metabolism Apolipoproteins E - metabolism Arteries - metabolism Atherosclerosis - diagnosis Atherosclerosis - metabolism Biomarkers - metabolism Contrast Media - administration & dosage Contrast Media - chemistry Cytokines - metabolism Drug Delivery Systems Female Interleukin-10 - metabolism Liposomes - administration & dosage Liposomes - chemistry Liposomes - pharmacokinetics Magnetic Resonance Imaging - methods Mice Mice, Inbred BALB C Microscopy, Confocal - methods Plaque, Atherosclerotic - diagnosis Plaque, Atherosclerotic - metabolism Polyethylene Glycols - administration & dosage Polyethylene Glycols - chemistry Recombinant Fusion Proteins - administration & dosage Spleen - drug effects Spleen - metabolism
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