Blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentration in essential tremor cases in Spain

► Environmental correlates for essential tremor (ET) are largely unexplored. ► Harmane (1-methyl-9H-pyrido[3,4-b]indole) is a potent tremor-producing toxin. ► Blood harmane levels were quantified by high performance liquid chromatography. ► Blood harmane levels were elevated in familial ET cases vs....

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Veröffentlicht in:	Neurotoxicology (Park Forest South) 2013-01, Vol.34, p.264-268
Hauptverfasser:	Louis, Elan D., Benito-León, Julian, Moreno-García, Sara, Vega, Saturio, Romero, Juan Pablo, Bermejo-Pareja, Felix, Gerbin, Marina, Viner, Amanda S., Factor-Litvak, Pam, Jiang, Wendy, Zheng, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Air. Soil. Water. Waste. Feeding Analysis of Variance Biological and medical sciences Case-Control Studies Chi-Square Distribution Chromatography, High Pressure Liquid Environment. Living conditions Environmental Pollutants - adverse effects Environmental Pollutants - blood Environmental risk factors Epidemiology Essential tremor Essential Tremor - blood Essential Tremor - chemically induced Essential Tremor - epidemiology Essential Tremor - physiopathology Female Harmane Harmine - adverse effects Harmine - analogs & derivatives Harmine - blood Humans Logistic Models Longitudinal Studies Male Medical sciences Middle Aged Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neurotoxicity Syndromes - blood Neurotoxicity Syndromes - epidemiology Neurotoxicity Syndromes - physiopathology Odds Ratio Public health. Hygiene Public health. Hygiene-occupational medicine Risk Assessment Risk Factors Spain - epidemiology Toxicology Toxin Up-Regulation β-Carboline alkaloid
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