Obesity-driven inflammation and cancer risk: role of myeloid derived suppressor cells and alternately activated macrophages
During carcinogenesis, tumors induce dysfunctional development of hematopoietic cells. Myeloid lineage cells, in the form of myeloid derived suppressor cells (MDSCs) and alternatively polarized M2 macrophages, influence almost all types of cancers by regulating diverse facets of immunosuppression, a...
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Veröffentlicht in: | American journal of cancer research 2013-01, Vol.3 (1), p.21-33 |
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