Prognostic Value of Promoter Hypermethylation of Retinoic Acid Receptor Beta (RARB) and CDKN2 (p16/MTS1) in Prostate Cancer

Objective: The molecular mechanism of prostate cancer is poorly understood. The aim of the study was to investigate the prevalence and prognostic value of promoter hypermethylation of retinoic acid receptor beta (RARB) and p16 among benign prostatic hyperplasia (BPH) and prostate cancer patients. Me...

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Veröffentlicht in:	Chinese journal of cancer research 2011-12, Vol.23 (4), p.306-311
Hauptverfasser:	Ameri, A., Alidoosti, A., Hosseini, Y., Parvin, M., Emranpour, M. H., Taslimi, F., Salehi, E., Fadavi, P.
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Sprache:	eng
Schlagworte:	Medicine Medicine & Public Health Original Original Article
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container_title	Chinese journal of cancer research
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creator	Ameri, A. Alidoosti, A. Hosseini, Y. Parvin, M. Emranpour, M. H. Taslimi, F. Salehi, E. Fadavi, P.
description	Objective: The molecular mechanism of prostate cancer is poorly understood. The aim of the study was to investigate the prevalence and prognostic value of promoter hypermethylation of retinoic acid receptor beta (RARB) and p16 among benign prostatic hyperplasia (BPH) and prostate cancer patients. Methods: In this case-control study, 63 patients were included in three groups; 21 with BPH as the control group, 21 with prostate cancer and good prognostic factors (based on prostate-specific antigen, Gleason sco...
doi_str_mv	10.1007/s11670-011-0306-x
format	Article
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title	Prognostic Value of Promoter Hypermethylation of Retinoic Acid Receptor Beta (RARB) and CDKN2 (p16/MTS1) in Prostate Cancer
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