Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy

To describe a severe form of demyelinating HIV-associated leukoencephalopathy in AIDS patients failing highly active antiretroviral therapy (HAART), its relationship to clinical and neuroimaging findings, and suggest hypotheses regarding pathogenesis. AIDS patients who failed HAART and displayed sev...

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Veröffentlicht in:	AIDS (London) 2002-05, Vol.16 (7), p.1019-1029
Hauptverfasser:	LANGFORD, T. Dianne, LETENDRE, Scott L, MASLIAH, Eliezer, MARCOTTE, Thomas D, ELLIS, Ronald J, MCCUTCHAN, J. Allen, GRANT, Igor, MALLORY, Margaret E, HANSEN, Lawrence A, ARCHIBALD, Sarah, JERNIGAN, Terry
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - drug therapy Adult AIDS Dementia Complex - pathology Antiretroviral Therapy, Highly Active - adverse effects Biological and medical sciences Brain - pathology Brain - virology CD4 Lymphocyte Count Cerebrospinal Fluid - virology Demyelinating Diseases - etiology Demyelinating Diseases - pathology Disease Progression Gliosis - etiology Gliosis - pathology HIV-1 - isolation & purification HIV-1 - physiology Human viral diseases Humans Infectious diseases Macrophages - immunology Macrophages - virology Magnetic Resonance Imaging Male Medical sciences Middle Aged Monocytes - immunology Monocytes - virology RNA, Viral - analysis Treatment Failure Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load Virus Replication
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