The Underlying Mechanisms of Endovascular Exclusion of Intracranial Aneurysms by Coils: How Important is Electrothrombosis?

Endovascular coil treatment of intracranial aneurysms is now widely accepted. We discuss some of the arguments for the relative roles of electrothrombosis, spontaneous thrombosis, mechanical filling, haemodynamic effects and surface properties in successful coil treatment. Despite an enormous body o...

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Veröffentlicht in:Interventional neuroradiology 2003-06, Vol.9 (2), p.127-140
Hauptverfasser: Henkes, H., Brew, S., Miloslavski, E., Fischer, S., Tavrovski, I., Hne, D. K.
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container_end_page 140
container_issue 2
container_start_page 127
container_title Interventional neuroradiology
container_volume 9
creator Henkes, H.
Brew, S.
Miloslavski, E.
Fischer, S.
Tavrovski, I.
Hne, D. K.
description Endovascular coil treatment of intracranial aneurysms is now widely accepted. We discuss some of the arguments for the relative roles of electrothrombosis, spontaneous thrombosis, mechanical filling, haemodynamic effects and surface properties in successful coil treatment. Despite an enormous body of literature, with many theories and much data, there is limited evidence for, or understanding of, the mechanisms by which coil treatment protects against aneurysm rupture. It seems likely that electrothrombosis plays no part. Dense packing is probably important in preventing recurrence. New technologies aiming to encourage endothelialisation and increased connective tissue formation appear promising.
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title The Underlying Mechanisms of Endovascular Exclusion of Intracranial Aneurysms by Coils: How Important is Electrothrombosis?
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