DNA damage due to oxidative stress in Chronic Obstructive Pulmonary Disease (COPD)

According to the American Thorasic Society (ATS)/European Respiratory Society (ERS) Statement, chronic obstructive pulmonary disease (COPD) is defined as a preventable and treatable disease with a strong genetic component, characterized by airflow limitation that is not fully reversible, but is usua...

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Veröffentlicht in:	International journal of molecular sciences 2012-12, Vol.13 (12), p.16853-16864
Hauptverfasser:	Neofytou, Eirini, Tzortzaki, Eleni G, Chatziantoniou, Argiro, Siafakas, Nikolaos M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveoli Animals Antigen-presenting cells Apoptosis Chronic obstructive pulmonary disease Cigarette smoke DNA damage DNA Damage - physiology DNA Repair - physiology Epithelium Gases Genomic Instability Humans Immune response Inflammation Lymphoid tissue Microsatellite Repeats - genetics Mutation Oxidative stress Oxidative Stress - physiology Parenchyma Proteolysis Pulmonary Disease, Chronic Obstructive - genetics Pulmonary Disease, Chronic Obstructive - metabolism Respiratory tract Review Senescence
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