Asymmetric dimethyarginine as marker and mediator in ischemic stroke

Asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase (NOS) inhibitor, is known as mediator of endothelial cell dysfunction and atherosclerosis. Circulating ADMA levels are correlated with cardiovascular risk factors such as hypercholesterolemia, arterial hypertension, diabetes mel...

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Veröffentlicht in:	International journal of molecular sciences 2012-11, Vol.13 (12), p.15983-16004
Hauptverfasser:	Chen, Shufen, Li, Na, Deb-Chatterji, Milani, Dong, Qiang, Kielstein, Jan T, Weissenborn, Karin, Worthmann, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - analogs & derivatives Arginine - metabolism Biomarkers - metabolism Brain Ischemia - metabolism Brain Ischemia - pathology Brain Ischemia - physiopathology Cerebrovascular Circulation Enzyme Inhibitors - metabolism Humans Methylation Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase - metabolism Oxidative Stress Protein Processing, Post-Translational Review Stroke - metabolism Stroke - pathology Stroke - physiopathology
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