Deficiency in Acellular Cementum and Periodontal Attachment in Bsp Null Mice

Bone sialoprotein (BSP) is an extracellular matrix protein found in mineralized tissues of the skeleton and dentition. BSP is multifunctional, affecting cell attachment and signaling through an RGD integrin-binding region, and acting as a positive regulator for mineral precipitation by nucleating hy...

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Veröffentlicht in:	Journal of dental research 2013-02, Vol.92 (2), p.166-172
Hauptverfasser:	Foster, B.L., Soenjaya, Y., Nociti, F.H., Holm, E., Zerfas, P.M., Wimer, H.F., Holdsworth, D.W., Aubin, J.E., Hunter, G.K., Goldberg, H.A., Somerman, M.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Alkaline Phosphatase - analysis Alveolar bone Alveolar Bone Loss - pathology Animals Bone resorption Bone sialoprotein Cell adhesion Cementogenesis - physiology Cementum Crystals Dental Cementum - pathology Dental occlusion Dental roots Dentin - ultrastructure Dentistry Dentition Epithelium - pathology Extracellular matrix Hydroxyapatite Incisor - ultrastructure Integrin-Binding Sialoprotein - genetics Integrin-Binding Sialoprotein - physiology Interfaces Keratins - analysis Matrix protein Mice Mice, Transgenic Microscopy, Electron, Scanning Mineralization Molar - ultrastructure Odontogenesis - genetics Odontogenesis - physiology Osteoclasts Osteoclasts - pathology Osteopontin - analysis Periodontal Attachment Loss - pathology Periodontal ligament Periodontal Ligament - pathology Proteins RANK Ligand - analysis Research Reports Root Resorption - pathology Scanning electron microscopy Skeleton Teeth Tooth Calcification - genetics Tooth Calcification - physiology Tooth Cervix - ultrastructure TRANCE protein X-Ray Microtomography
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