Neurovascular saturation thresholds under high intensity auditory stimulation during wake

Highlights ► We measured auditory-evoked electrical and hemodynamic responses during wake. ► We varied the stimulus intensity to investigate potential perfusion limits. ► At higher intensity stimulation, the evoked electrical response size increased. ► At higher intensity stimulation, the evoked hem...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2012-12, Vol.227, p.191-200
Hauptverfasser:	Schei, J.L, Van Nortwick, A.S, Meighan, P.C, Rector, D.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Animals Biological and medical sciences Cerebrovascular Circulation - physiology Electroencephalography ERP Evoked Potentials, Auditory - physiology Female Fundamental and applied biological sciences. Psychology Hemoglobins - metabolism Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Neurology neurovascular coupling NIRS Oxyhemoglobins - metabolism Psychoacoustics Rats Rats, Sprague-Dawley Vertebrates: nervous system and sense organs Wakefulness - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights ► We measured auditory-evoked electrical and hemodynamic responses during wake. ► We varied the stimulus intensity to investigate potential perfusion limits. ► At higher intensity stimulation, the evoked electrical response size increased. ► At higher intensity stimulation, the evoked hemodynamic response size plateaued. ► There may be decreased vascular compliance during wake, limiting blood perfusion.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2012.09.060