PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage

p53 has a crucial role in governing cellular mechanisms in response to a broad range of genotoxic stresses. During DNA damage, p53 can either promote cell survival by activating senescence or cell-cycle arrest and DNA repair to maintain genomic integrity for cell survival or direct cells to undergo...

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Veröffentlicht in:Cell death & disease 2012-12, Vol.3 (12), p.e442-e442
Hauptverfasser: Huang, B H, Zhuo, J L, Leung, C H W, Lu, G D, Liu, J J, Yap, C T, Hooi, S C
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Sprache:eng
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