Memory-Based Strategies for Antiretroviral Medication Management: An Evaluation of Clinical Predictors, Adherence Behavior Awareness, and Effectiveness
“Forgetting” is the most commonly endorsed reason for missing an antiretroviral therapy (ART) dose, yet little is known about the prevalence, predictors, and effectiveness of the mnemonic strategies to support ART adherence. The current study assessed 28 self-reported memory-based medication strateg...
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Veröffentlicht in: | AIDS and behavior 2013, Vol.17 (1), p.74-85 |
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description | “Forgetting” is the most commonly endorsed reason for missing an antiretroviral therapy (ART) dose, yet little is known about the prevalence, predictors, and effectiveness of the mnemonic strategies to support ART adherence. The current study assessed 28 self-reported memory-based medication strategies in 233 HIV-infected individuals with 30-day ART adherence measured via the medication event monitoring system. Participants endorsed using multiple (8.7 ± 5.6) strategies with the most common being internally-driven. More frequent strategy use was uniquely associated with affective distress, dependent daily functioning, higher non-ART pill burden, and poorer ART adherence. Individuals who used strategies frequently, but perceived them as minimally effective, had more affective, physical, and functional distress. More frequent strategy use was associated with worse ART adherence and was unrelated to perceived effectiveness. Primary reliance on internally-based mnemonic strategies may reflect a lack of awareness of adherence behaviors and may be insufficient to support optimal ART adherence in vulnerable populations. |
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P. ; Weber, E. ; Grant, I. ; Moore, D. J.</creator><creatorcontrib>Blackstone, K. ; Woods, S. P. ; Weber, E. ; Grant, I. ; Moore, D. J. ; HNRP Group ; The HNRP Group</creatorcontrib><description>“Forgetting” is the most commonly endorsed reason for missing an antiretroviral therapy (ART) dose, yet little is known about the prevalence, predictors, and effectiveness of the mnemonic strategies to support ART adherence. The current study assessed 28 self-reported memory-based medication strategies in 233 HIV-infected individuals with 30-day ART adherence measured via the medication event monitoring system. Participants endorsed using multiple (8.7 ± 5.6) strategies with the most common being internally-driven. More frequent strategy use was uniquely associated with affective distress, dependent daily functioning, higher non-ART pill burden, and poorer ART adherence. Individuals who used strategies frequently, but perceived them as minimally effective, had more affective, physical, and functional distress. More frequent strategy use was associated with worse ART adherence and was unrelated to perceived effectiveness. Primary reliance on internally-based mnemonic strategies may reflect a lack of awareness of adherence behaviors and may be insufficient to support optimal ART adherence in vulnerable populations.</description><identifier>ISSN: 1090-7165</identifier><identifier>EISSN: 1573-3254</identifier><identifier>DOI: 10.1007/s10461-012-0308-9</identifier><identifier>PMID: 22968399</identifier><identifier>CODEN: AIBEFC</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Activities of Daily Living ; Adult ; Anti-HIV Agents - administration & dosage ; Anti-HIV Agents - therapeutic use ; Antiretroviral agents ; Antiretroviral drugs ; Antiviral agents ; Awareness ; Consciousness ; Drug use ; Effectiveness studies ; Female ; Health Behavior ; Health Psychology ; HIV ; HIV Infections - drug therapy ; HIV Infections - psychology ; Human immunodeficiency virus ; Humans ; Infectious Diseases ; Male ; Management ; Medication Adherence - psychology ; Medication Adherence - statistics & numerical data ; Medications ; Medicine ; Medicine & Public Health ; Memory ; Middle Aged ; Neuropsychological Tests ; Original Paper ; Predictive Value of Tests ; Prevalence ; Psychiatric Status Rating Scales ; Psychological Distress ; Public Health ; Reminder Systems - statistics & numerical data ; Risk Factors ; Self awareness ; Self Report ; Socioeconomic Factors ; Vulnerability</subject><ispartof>AIDS and behavior, 2013, Vol.17 (1), p.74-85</ispartof><rights>Springer Science+Business Media, LLC 2012</rights><rights>Springer Science+Business Media New York 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c536t-e27af5b3d135f073dec0291edbeabc7104c864e2be52995f26a9f16d62969eb3</citedby><cites>FETCH-LOGICAL-c536t-e27af5b3d135f073dec0291edbeabc7104c864e2be52995f26a9f16d62969eb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10461-012-0308-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10461-012-0308-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,777,781,882,27325,27905,27906,33755,33756,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22968399$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Blackstone, K.</creatorcontrib><creatorcontrib>Woods, S. P.</creatorcontrib><creatorcontrib>Weber, E.</creatorcontrib><creatorcontrib>Grant, I.</creatorcontrib><creatorcontrib>Moore, D. J.</creatorcontrib><creatorcontrib>HNRP Group</creatorcontrib><creatorcontrib>The HNRP Group</creatorcontrib><title>Memory-Based Strategies for Antiretroviral Medication Management: An Evaluation of Clinical Predictors, Adherence Behavior Awareness, and Effectiveness</title><title>AIDS and behavior</title><addtitle>AIDS Behav</addtitle><addtitle>AIDS Behav</addtitle><description>“Forgetting” is the most commonly endorsed reason for missing an antiretroviral therapy (ART) dose, yet little is known about the prevalence, predictors, and effectiveness of the mnemonic strategies to support ART adherence. The current study assessed 28 self-reported memory-based medication strategies in 233 HIV-infected individuals with 30-day ART adherence measured via the medication event monitoring system. Participants endorsed using multiple (8.7 ± 5.6) strategies with the most common being internally-driven. More frequent strategy use was uniquely associated with affective distress, dependent daily functioning, higher non-ART pill burden, and poorer ART adherence. Individuals who used strategies frequently, but perceived them as minimally effective, had more affective, physical, and functional distress. More frequent strategy use was associated with worse ART adherence and was unrelated to perceived effectiveness. Primary reliance on internally-based mnemonic strategies may reflect a lack of awareness of adherence behaviors and may be insufficient to support optimal ART adherence in vulnerable populations.</description><subject>Activities of Daily Living</subject><subject>Adult</subject><subject>Anti-HIV Agents - administration & dosage</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Antiretroviral agents</subject><subject>Antiretroviral drugs</subject><subject>Antiviral agents</subject><subject>Awareness</subject><subject>Consciousness</subject><subject>Drug use</subject><subject>Effectiveness studies</subject><subject>Female</subject><subject>Health Behavior</subject><subject>Health Psychology</subject><subject>HIV</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - psychology</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Male</subject><subject>Management</subject><subject>Medication Adherence - psychology</subject><subject>Medication Adherence - statistics & numerical data</subject><subject>Medications</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Memory</subject><subject>Middle Aged</subject><subject>Neuropsychological Tests</subject><subject>Original Paper</subject><subject>Predictive Value of Tests</subject><subject>Prevalence</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychological Distress</subject><subject>Public Health</subject><subject>Reminder Systems - statistics & numerical data</subject><subject>Risk Factors</subject><subject>Self awareness</subject><subject>Self Report</subject><subject>Socioeconomic Factors</subject><subject>Vulnerability</subject><issn>1090-7165</issn><issn>1573-3254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>BHHNA</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkstu1DAUhiMEohd4ADbIEhsWDfgS2zELpOlouEgdgUT3luOczLhK7GIng_okvC4OKVVBQrCy5f87__E5-oviGcGvCMbydSK4EqTEhJaY4bpUD4pjwiUrGeXVw3zHCpeSCH5UnKR0hTFWQqrHxRGlStRMqePi-xaGEG_Kc5OgRV_GaEbYOUioCxGt_OgijDEcXDQ92kLrrBld8GhrvNnBAH58kym0OZh-WpTQoXXvfAZ79DnOFWOI6Qyt2j1E8BbQOezNwc3230x-gZRV41u06Tqwozv8fHpSPOpMn-Dp7XlaXL7bXK4_lBef3n9cry5Ky5kYS6DSdLxhLWG8w5K1YDFVBNoGTGNl3o-tRQW0AU6V4h0VRnVEtCIvQEHDTou3i-311AzQ2jxQnlRfRzeYeKODcfp3xbu93oWDZpzVBLNs8PLWIIavE6RRDy5Z6HvjIUxJk6qqlZKKyn-j-eOCMELr_0BrXglKKpHRF3-gV2GKPu8sU5LUCtdy7k0WysaQUoTubkSC9ZwlvWRJ5yzpOUta5Zrn93dzV_ErPBmgC5Cy5HcQ77X-q-sPEBXWww</recordid><startdate>2013</startdate><enddate>2013</enddate><creator>Blackstone, K.</creator><creator>Woods, S. 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P.</au><au>Weber, E.</au><au>Grant, I.</au><au>Moore, D. J.</au><aucorp>HNRP Group</aucorp><aucorp>The HNRP Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Memory-Based Strategies for Antiretroviral Medication Management: An Evaluation of Clinical Predictors, Adherence Behavior Awareness, and Effectiveness</atitle><jtitle>AIDS and behavior</jtitle><stitle>AIDS Behav</stitle><addtitle>AIDS Behav</addtitle><date>2013</date><risdate>2013</risdate><volume>17</volume><issue>1</issue><spage>74</spage><epage>85</epage><pages>74-85</pages><issn>1090-7165</issn><eissn>1573-3254</eissn><coden>AIBEFC</coden><abstract>“Forgetting” is the most commonly endorsed reason for missing an antiretroviral therapy (ART) dose, yet little is known about the prevalence, predictors, and effectiveness of the mnemonic strategies to support ART adherence. The current study assessed 28 self-reported memory-based medication strategies in 233 HIV-infected individuals with 30-day ART adherence measured via the medication event monitoring system. Participants endorsed using multiple (8.7 ± 5.6) strategies with the most common being internally-driven. More frequent strategy use was uniquely associated with affective distress, dependent daily functioning, higher non-ART pill burden, and poorer ART adherence. Individuals who used strategies frequently, but perceived them as minimally effective, had more affective, physical, and functional distress. More frequent strategy use was associated with worse ART adherence and was unrelated to perceived effectiveness. Primary reliance on internally-based mnemonic strategies may reflect a lack of awareness of adherence behaviors and may be insufficient to support optimal ART adherence in vulnerable populations.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>22968399</pmid><doi>10.1007/s10461-012-0308-9</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Activities of Daily Living Adult Anti-HIV Agents - administration & dosage Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiviral agents Awareness Consciousness Drug use Effectiveness studies Female Health Behavior Health Psychology HIV HIV Infections - drug therapy HIV Infections - psychology Human immunodeficiency virus Humans Infectious Diseases Male Management Medication Adherence - psychology Medication Adherence - statistics & numerical data Medications Medicine Medicine & Public Health Memory Middle Aged Neuropsychological Tests Original Paper Predictive Value of Tests Prevalence Psychiatric Status Rating Scales Psychological Distress Public Health Reminder Systems - statistics & numerical data Risk Factors Self awareness Self Report Socioeconomic Factors Vulnerability |
title | Memory-Based Strategies for Antiretroviral Medication Management: An Evaluation of Clinical Predictors, Adherence Behavior Awareness, and Effectiveness |
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