Interaction between serine phosphorylated IRS-1 and β1-integrin affects the stability of neuronal processes

Tumor necrosis factor‐α (TNFα) released in the brain by HIV‐activated macrophages/microglia is suspected to compromise neuronal survival. Previously, we have demonstrated that activated receptor for insulin‐like growth factor I (IGF‐IR) protects neurons from TNFα‐induced neuronal damage (Wang et al....

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Veröffentlicht in:	Journal of neuroscience research 2007-08, Vol.85 (11), p.2360-2373
Hauptverfasser:	Wang, Jin Ying, Gualco, Elisa, Peruzzi, Francesca, Sawaya, Bassel E., Passiatore, Giovanni, Marcinkiewicz, Cezary, Staniszewska, Izabella, Ferrante, Pasquale, Amini, Shohreh, Khalili, Kamel, Reiss, Krzysztof
Format:	Artikel
Sprache:	eng
Schlagworte:	IGF-I integrins IRS-1 neuronal damage TNFα
Online-Zugang:	Volltext
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