Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage

Previous studies have demonstrated that aneuploidy in human embryos is surprisingly frequent with 50–80% of cleavage-stage human embryos carrying an abnormal chromosome number. Here we combine non-invasive time-lapse imaging with karyotypic reconstruction of all blastomeres in four-cell human embryo...

Ausführliche Beschreibung