Influence of different commercial scaffolds on the in vitro differentiation of human mesenchymal stem cells to nucleus pulposus-like cells

Introduction Cell-based therapies for regeneration of the degenerated intervertebral disc (IVD) are an alternative to current surgical intervention. Mesenchymal stem cells (MSCs), in combination with a scaffold, might be ideal candidates for regenerating nucleus pulposus (NP), the pressure-distribut...

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Veröffentlicht in:	European spine journal 2012-08, Vol.21 (Suppl 6), p.826-838
Hauptverfasser:	Bertolo, Alessandro, Mehr, Marco, Aebli, Niklaus, Baur, Martin, Ferguson, Stephen J., Stoyanov, Jivko V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Cell Differentiation Cells, Cultured Chitosan Female Gelatin Horses Humans In Vitro Techniques Intervertebral Disc - cytology Intervertebral Disc - metabolism Intervertebral Disc Degeneration - therapy Male Medicine Medicine & Public Health Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Neurosurgery Original Original Article Proteoglycans - metabolism Surgical Orthopedics Swine Tissue Scaffolds Young Adult
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