TGF‐β‐Superfamily Signaling Regulates Embryonic Stem Cell Heterogeneity: Self‐Renewal as a Dynamic and Regulated Equilibrium

Embryonic stem cells dynamically fluctuate between phenotypic states, as defined by expression levels of genes such as Nanog, while remaining pluripotent. The dynamic phenotype of stem cells is in part determined by gene expression control and dictated by various signaling pathways and transcription...

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Veröffentlicht in:Stem cells (Dayton, Ohio) Ohio), 2013-01, Vol.31 (1), p.48-58
Hauptverfasser: Galvin‐Burgess, Katherine E., Travis, Emily D., Pierson, Kelsey E., Vivian, Jay L.
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Sprache:eng
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