A Novel Mode of Regulation of the Staphylococcus aureus Catabolite Control Protein A (CcpA) Mediated by Stk1 Protein Phosphorylation

The Staphylococcus aureus serine/threonine protein kinase Stk1 (also known as PknB) affects different key pathways such as cell wall metabolism, antibiotic susceptibility, and regulation of virulence. Here we report that the catabolite control protein A (CcpA), a highly conserved regulator of carbon...

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Veröffentlicht in:	The Journal of biological chemistry 2012-12, Vol.287 (52), p.43607-43619
Hauptverfasser:	Leiba, Jade, Hartmann, Torsten, Cluzel, Marie-Eve, Cohen-Gonsaud, Martin, Delolme, Frédéric, Bischoff, Markus, Molle, Virginie
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Bacillus subtilis - physiology Bacterial Proteins - biosynthesis Bacterial Proteins - genetics Bacteriology Biofilms - growth & development Escherichia coli - physiology Gene Expression Regulation, Bacterial - physiology Life Sciences Microbiology Microbiology and Parasitology Mutation, Missense Phosphorylation - physiology Prokaryotic Protein Kinases Prokaryotic Signal Transduction Protein-Serine-Threonine Kinases - biosynthesis Protein-Serine-Threonine Kinases - genetics Repressor Proteins - biosynthesis Repressor Proteins - genetics Serine/Threonine Protein Kinase Staphylococcus aureus Staphylococcus aureus - physiology Transcription, Genetic - physiology Virulence Factors Virulence Factors - biosynthesis Virulence Factors - genetics
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