Hypoxia-inducible factor-1α overexpression indicates poor clinical outcomes in tongue squamous cell carcinoma

The aim of the present study was to investigate the expression of hypoxia-inducible factor-1α (HIF-1α) in tongue squamous cell carcinoma (TSCC) and to assess its possible impact on prognosis. A total of 49 tumor samples and 15 adjacent non-tumor samples from 49 patients treated between January 2000...

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Veröffentlicht in:	Experimental and therapeutic medicine 2013-01, Vol.5 (1), p.112-118
Hauptverfasser:	KANG, FEI-WU, GAO, YIN, QUE, LIN, SUN, JING, WANG, ZUO-LIN
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Breast cancer Clinical outcomes Gene amplification Hypoxia hypoxia-inducible factor-1α Lymphatic system Medical prognosis Metastasis prognosis Proteins Squamous cell carcinoma Studies Tomography tongue squamous cell carcinoma Tumors Vascular endothelial growth factor
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