Dynamic Sensory Representations in the Olfactory Bulb: Modulation by Wakefulness and Experience

How are sensory representations in the brain influenced by the state of an animal? Here we use chronic two-photon calcium imaging to explore how wakefulness and experience shape odor representations in the mouse olfactory bulb. Comparing the awake and anesthetized state, we show that wakefulness gre...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2012-12, Vol.76 (5), p.962-975
Hauptverfasser:	Kato, Hiroyuki K., Chu, Monica W., Isaacson, Jeffry S., Komiyama, Takaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Action Potentials - genetics Animals Animals, Newborn Brain Cadherins - genetics Calmodulin - genetics Calmodulin - metabolism Glutamate Decarboxylase - genetics Green Fluorescent Proteins - genetics Humans Mice Mice, Inbred C57BL Mice, Transgenic Models, Biological Nerve Tissue Proteins - genetics Neuronal Plasticity - genetics Neuronal Plasticity - physiology Neurons Neurons - physiology Nonlinear Dynamics Odorants Odors Olfactory Bulb - cytology Olfactory Bulb - physiology Olfactory Marker Protein - genetics Olfactory Pathways - physiology Smell - physiology Studies Time Factors Wakefulness - physiology
Online-Zugang:	Volltext
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