Differential neurite outgrowth is required for axon specification by cultured hippocampal neurons

Formation of an axon is the first morphological evidence of neuronal polarization, visible as a profound outgrowth of the axon compared with sibling neurites. One unsolved question on the mechanism of axon formation is the role of axon outgrowth in axon specification. This question was difficult to...

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Veröffentlicht in:	Journal of neurochemistry 2012-12, Vol.123 (6), p.904-910
Hauptverfasser:	Yamamoto, Hideaki, Demura, Takanori, Morita, Mayu, Banker, Gary A., Tanii, Takashi, Nakamura, Shun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Axonogenesis Axons - physiology Biological and medical sciences Brain Cell culture Cellular biology Female Fetus - cytology Fetus - physiology Fundamental and applied biological sciences. Psychology Growth Cones - physiology hippocampal neuron Hippocampus Hippocampus - cytology Hippocampus - physiology Isolated neuron and nerve. Neuroglia kinesin live-cell imaging Medical sciences micropatterned surface Miscellaneous. Antibiotics with multiple activities Neurites - physiology Neurochemistry neuronal polarization Neurons Neurons - physiology Neurons - ultrastructure Pharmacology. Drug treatments Polarization Pregnancy Primary Cell Culture Rats Rats, Sprague-Dawley Siblings Vertebrates: nervous system and sense organs
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