Imbalance of Angiopoietin-1 and Angiopoetin-2 in Severe Dengue and Relationship with Thrombocytopenia, Endothelial Activation, and Vascular Stability

The pathogenesis of plasma leakage during dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) is largely unknown. Angiopoietins are key regulators of vascular integrity: Angiopoietin-1 is stored in platelets and maintains vascular integrity, and endothelium-derived angiopoietin-2 promotes vascu...

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Veröffentlicht in:The American journal of tropical medicine and hygiene 2012-11, Vol.87 (5), p.943-946
Hauptverfasser: MICHELS, Meta, VAN DER VEN, André J. A. M. Van, DJAMIATUN, Kis, FIJNHEER, Rob, DE GROOT, Philip G, GRIFFIOEN, Arjan W, SEBASTIAN, Silvie, FARADZ, Sultana M. H, DE MAST, Quirijn
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Sprache:eng
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