Small serotonin-positive pancreatic endocrine tumors caused obstruction of the main pancreatic duct
We report 2 cases of pancreatic endocrine tumors that caused obstruction of the main pancreatic duct（MPD）.A 49-year-old asymptomatic man was referred to our institution because dilation of the MPD was revealed by abdominal ultrasonography（US）.No tumor was detected by endoscopic ultrasonography,compu...
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| Veröffentlicht in: | World journal of gastroenterology : WJG 2012-12, Vol.18 (45), p.6669-6673 |
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| container_title | World journal of gastroenterology : WJG |
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| creator | Ogawa, Masami Kawaguchi, Yoshiaki Maruno, Atsuko Ito, Hiroyuki Nakagohri, Toshio Hirabayashi, Kenichi Yamamuro, Hiroshi Yamashita, Tomohiro Mine, Tetsuya |
| description | We report 2 cases of pancreatic endocrine tumors that caused obstruction of the main pancreatic duct（MPD）.A 49-year-old asymptomatic man was referred to our institution because dilation of the MPD was revealed by abdominal ultrasonography（US）.No tumor was detected by endoscopic ultrasonography,computed tomography（CT）,and magnetic resonance imaging（MRI）.The diameter of the MPD was 〉 20 mm at the body,and no dilation was noted at the head.Although malignancy was not confirmed through cytology or imaging,pancreatic cancer was strongly suspected.Pancreaticoduo-denectomy was performed.Pathological and immunohistochemical examination revealed a 5 mm × 3 mm serotonin-positive endocrine tumor.Fibrosis was present around the MPD and seemed to cause stricture.A 32-year-old asymptomatic man had elevated serum amylase,and US demonstrated dilation of the MPD.No tumor was detected by CT and MRI.Pancreatic cancer was suspected due to stricture and dilation of the MPD.Pancreatectomy of middle part of pancreas was performed.Pathological and immunohistochemical examination revealed a serotonin-positive endocrine tumor sized 5 mm × 4 mm.We report 2 cases of serotonin-positive pancreatic endocrine tumors that caused stricture of the MPD in spite of the small size of the tumor. |
| doi_str_mv | 10.3748/wjg.v18.i45.6669 |
| format | Article |
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surgery</subject><subject>Pancreatic Neoplasms - diagnostic imaging</subject><subject>Pancreatic Neoplasms - metabolism</subject><subject>Pancreatitis - surgery</subject><subject>Serotonin - metabolism</subject><subject>Tomography, X-Ray Computed</subject><subject>Ultrasonography</subject><subject>内分泌</subject><subject>恶性肿瘤</subject><subject>梗阻</subject><subject>病理组织学</subject><subject>羟色胺</subject><subject>胰管</subject><subject>胰腺癌</subject><subject>阳性</subject><issn>1007-9327</issn><issn>2219-2840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkT1vFDEQhi0EIkegp0Kmo9nD9vhrGyQUAUGKRAHUltfrvXO0a19s7yH-PY5ynJJqinned0Z6EHpLyRYU1x__3O62R6q3gYutlLJ_hjaM0b5jmpPnaEMJUV0PTF2gV6XcEsIABHuJLhgwkIzDBrmfi51nXHxONcUQu0MqoYajxwcbXfa2Bod9HJPLIXpc1yXlgp1dix9xGkrNq6shRZwmXPceLzbEx9GxrV-jF5Odi39zmpfo99cvv66uu5sf375ffb7pHNe6dpTJaeinQRHtvQShQfcj1YMTfBgJ04oxwkQ_Og89B67FNIIGIriXyklh4RJ9eug9rMPiGxdrtrM55LDY_NckG8zTTQx7s0tHA4JKRqAVfDgV5HS3-lLNEorz82yjT2sxlEFPhNJUNpQ8oC6nUrKfzmcoMfduTHNjmhvT3Jh7Ny3y7vF758B_GQ14f-rcp7i7C3F3ZjjnhGil4B9Wqplu</recordid><startdate>20121207</startdate><enddate>20121207</enddate><creator>Ogawa, Masami</creator><creator>Kawaguchi, Yoshiaki</creator><creator>Maruno, Atsuko</creator><creator>Ito, Hiroyuki</creator><creator>Nakagohri, Toshio</creator><creator>Hirabayashi, Kenichi</creator><creator>Yamamuro, Hiroshi</creator><creator>Yamashita, Tomohiro</creator><creator>Mine, Tetsuya</creator><general>Baishideng Publishing Group Co., Limited</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20121207</creationdate><title>Small serotonin-positive pancreatic endocrine tumors caused obstruction of the main pancreatic duct</title><author>Ogawa, Masami ; Kawaguchi, Yoshiaki ; Maruno, Atsuko ; Ito, Hiroyuki ; Nakagohri, Toshio ; Hirabayashi, Kenichi ; Yamamuro, Hiroshi ; Yamashita, Tomohiro ; Mine, Tetsuya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c488t-126fb9fb708ee6358389d18bc54bd0287220259dce3943485fd383054e67c65a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Case Report</topic><topic>Cholangiopancreatography, Endoscopic Retrograde</topic><topic>Diagnosis, Differential</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pancreatic Ducts - surgery</topic><topic>Pancreatic Neoplasms - diagnostic imaging</topic><topic>Pancreatic Neoplasms - metabolism</topic><topic>Pancreatitis - surgery</topic><topic>Serotonin - metabolism</topic><topic>Tomography, X-Ray Computed</topic><topic>Ultrasonography</topic><topic>内分泌</topic><topic>恶性肿瘤</topic><topic>梗阻</topic><topic>病理组织学</topic><topic>羟色胺</topic><topic>胰管</topic><topic>胰腺癌</topic><topic>阳性</topic><toplevel>online_resources</toplevel><creatorcontrib>Ogawa, Masami</creatorcontrib><creatorcontrib>Kawaguchi, Yoshiaki</creatorcontrib><creatorcontrib>Maruno, Atsuko</creatorcontrib><creatorcontrib>Ito, Hiroyuki</creatorcontrib><creatorcontrib>Nakagohri, Toshio</creatorcontrib><creatorcontrib>Hirabayashi, Kenichi</creatorcontrib><creatorcontrib>Yamamuro, Hiroshi</creatorcontrib><creatorcontrib>Yamashita, Tomohiro</creatorcontrib><creatorcontrib>Mine, Tetsuya</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>World journal of gastroenterology : WJG</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ogawa, Masami</au><au>Kawaguchi, Yoshiaki</au><au>Maruno, Atsuko</au><au>Ito, Hiroyuki</au><au>Nakagohri, Toshio</au><au>Hirabayashi, Kenichi</au><au>Yamamuro, Hiroshi</au><au>Yamashita, Tomohiro</au><au>Mine, Tetsuya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Small serotonin-positive pancreatic endocrine tumors caused obstruction of the main pancreatic duct</atitle><jtitle>World journal of gastroenterology : WJG</jtitle><addtitle>World Journal of Gastroenterology</addtitle><date>2012-12-07</date><risdate>2012</risdate><volume>18</volume><issue>45</issue><spage>6669</spage><epage>6673</epage><pages>6669-6673</pages><issn>1007-9327</issn><eissn>2219-2840</eissn><abstract>We report 2 cases of pancreatic endocrine tumors that caused obstruction of the main pancreatic duct（MPD）.A 49-year-old asymptomatic man was referred to our institution because dilation of the MPD was revealed by abdominal ultrasonography（US）.No tumor was detected by endoscopic ultrasonography,computed tomography（CT）,and magnetic resonance imaging（MRI）.The diameter of the MPD was 〉 20 mm at the body,and no dilation was noted at the head.Although malignancy was not confirmed through cytology or imaging,pancreatic cancer was strongly suspected.Pancreaticoduo-denectomy was performed.Pathological and immunohistochemical examination revealed a 5 mm × 3 mm serotonin-positive endocrine tumor.Fibrosis was present around the MPD and seemed to cause stricture.A 32-year-old asymptomatic man had elevated serum amylase,and US demonstrated dilation of the MPD.No tumor was detected by CT and MRI.Pancreatic cancer was suspected due to stricture and dilation of the MPD.Pancreatectomy of middle part of pancreas was performed.Pathological and immunohistochemical examination revealed a serotonin-positive endocrine tumor sized 5 mm × 4 mm.We report 2 cases of serotonin-positive pancreatic endocrine tumors that caused stricture of the MPD in spite of the small size of the tumor.</abstract><cop>United States</cop><pub>Baishideng Publishing Group Co., Limited</pub><pmid>23236243</pmid><doi>10.3748/wjg.v18.i45.6669</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | World journal of gastroenterology : WJG, 2012-12, Vol.18 (45), p.6669-6673 |
| issn | 1007-9327 2219-2840 |
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| source | MEDLINE; Baishideng "World Journal of" online journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Case Report Cholangiopancreatography, Endoscopic Retrograde Diagnosis, Differential Humans Immunohistochemistry Magnetic Resonance Imaging Male Middle Aged Pancreatic Ducts - surgery Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - metabolism Pancreatitis - surgery Serotonin - metabolism Tomography, X-Ray Computed Ultrasonography 内分泌 恶性肿瘤 梗阻 病理组织学 羟色胺 胰管 胰腺癌 阳性 |
| title | Small serotonin-positive pancreatic endocrine tumors caused obstruction of the main pancreatic duct |
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