Chromothripsis: Chromosomes in Crisis

During oncogenesis, cells acquire multiple genetic alterations that confer essential tumor-specific traits, including immortalization, escape from antimitogenic signaling, neovascularization, invasiveness, and metastatic potential. In most instances, these alterations are thought to arise incrementa...

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Veröffentlicht in:	Developmental cell 2012-11, Vol.23 (5), p.908-917
Hauptverfasser:	Jones, Mathew J.K., Jallepalli, Prasad V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Chromosomal Instability Chromosome Aberrations Chromosome Breakage DNA Repair DNA Replication Gene Rearrangement Humans Mitosis Models, Genetic Mutation Neoplasms - etiology Neoplasms - genetics Telomere Shortening
Online-Zugang:	Volltext
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