Types, causes, detection and repair of DNA fragmentation in animal and human sperm cells

Concentration, motility and morphology are parameters commonly used to determine the fertilization potential of an ejaculate. These parameters give a general view on the quality of sperm but do not provide information about one of the most important components of the reproductive outcome: DNA. Eithe...

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Veröffentlicht in:	International journal of molecular sciences 2012-10, Vol.13 (11), p.14026-14052
Hauptverfasser:	González-Marín, Clara, Gosálvez, Jaime, Roy, Rosa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Chromatin DNA Breaks, Double-Stranded DNA Breaks, Single-Stranded DNA Damage DNA Fragmentation DNA Repair Ejaculation Embryonic Development - genetics Embryos Epididymis Female Fertilization Fertilization - genetics Humans Infection Male Motility Oocytes Oocytes - metabolism Oxidative stress protamine Recombination Review Reviews Somatic cells Sperm Spermatozoa - metabolism Temperature effects Transcription Translation
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