The Interface between BCR-ABL-Dependent and -Independent Resistance Signaling Pathways in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a clonal hematopoietic disorder characterized by the presence of the Philadelphia chromosome which resulted from the reciprocal translocation between chromosomes 9 and 22. The pathogenesis of CML involves the constitutive activation of the BCR-ABL tyrosine kinase, w...

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Veröffentlicht in:	Leukemia Research and Treatment 2012-01, Vol.2012 (2012), p.151-169
Hauptverfasser:	Nestal de Moraes, Gabriela, Souza, Paloma Silva, Costas, Fernanda Casal de Faria, Vasconcelos, Flavia Cunha, Reis, Flaviana Ruade Souza, Maia, Raquel Ciuvalschi
Format:	Artikel
Sprache:	eng
Schlagworte:	Review
Online-Zugang:	Volltext
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