Distribution of angiotensin type 1a receptor-containing cells in the brains of bacterial artificial chromosome transgenic mice

Highlights ► Agtr1a BAC transgenic mice express cells with angiotensin 1A receptors with fidelity. ► In Agtr1a BAC transgenic mice, labeled cells are prominent in brain autonomic regions. ► Labeled cells from these mice are suitable for anatomical and physiological studies.

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2012-12, Vol.226, p.489-509
Hauptverfasser:	Gonzalez, A.D, Wang, G, Waters, E.M, Gonzales, K.L, Speth, R.C, Van Kempen, T.A, Marques-Lopes, J, Young, C.N, Butler, S.D, Davisson, R.L, Iadecola, C, Pickel, V.M, Pierce, J.P, Milner, T.A
Format:	Artikel
Sprache:	eng
Schlagworte:	amygdala Animals Arginine Vasopressin - immunology Arginine Vasopressin - metabolism Autonomic Nervous System - cytology Autonomic Nervous System - metabolism autonomic nuclei Biological and medical sciences Brain - cytology Brain Chemistry - genetics Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Chromosomes, Artificial, Bacterial - genetics Fundamental and applied biological sciences. Psychology Green Fluorescent Proteins - genetics Green Fluorescent Proteins - immunology Humans hypothalamus Image Processing, Computer-Assisted Immunoenzyme Techniques Immunohistochemistry Mice Mice, Transgenic Microscopy, Electron Microscopy, Immunoelectron Neurology nucleus of the solitary tract Reactive Oxygen Species - metabolism Receptor, Angiotensin, Type 1 - metabolism RNA, Messenger - biosynthesis RNA, Messenger - genetics rostral ventrolateral medulla subfornical organ Tyrosine 3-Monooxygenase - metabolism Vertebrates: nervous system and sense organs Water-Electrolyte Balance - genetics Water-Electrolyte Balance - physiology
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Beschreibung
Zusammenfassung:	Highlights ► Agtr1a BAC transgenic mice express cells with angiotensin 1A receptors with fidelity. ► In Agtr1a BAC transgenic mice, labeled cells are prominent in brain autonomic regions. ► Labeled cells from these mice are suitable for anatomical and physiological studies.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2012.08.039