c-Myc and cancer metabolism

The processes of cellular growth regulation and cellular metabolism are closely interrelated. The c-Myc oncogene is a "master regulator" which controls many aspects of both of these processes. The metabolic changes which occur in transformed cells, many of which are driven by c-Myc overexp...

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Veröffentlicht in:	Clinical cancer research 2012-10, Vol.18 (20), p.5546-5553
Hauptverfasser:	Miller, Donald M, Thomas, Shelia D, Islam, Ashraful, Muench, David, Sedoris, Kara
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Proliferation Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Gene Expression Regulation, Neoplastic Glutamine - metabolism Glycolysis Humans Mitochondria - metabolism Molecular Targeted Therapy Neoplasms - genetics Neoplasms - metabolism Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism
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